DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Atg3 and Atg3

Sequence 1:NP_649059.1 Gene:Atg3 FlyBaseID:FBgn0036813 Length:330 Species:Drosophila melanogaster
Sequence 2:NP_080678.1 Gene:Atg3 MGIID:1915091 Length:314 Species:Mus musculus

Alignment Length:331 Identity:208/332 (63%)
Similarity:259/332 (78%) Gaps:19/332 (6%)


  Fly     1 MQSVLNTVKGTALNVAEYLTPVLKESKFRETGVLTPEEFVAAGDHLVHHCPTWQWAAGDETKTKP 65
            ||:|:|||||.||.||||||||||||||:||||:||||||||||||||||||||||.|:|.|.|.
Mouse     1 MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKA 65

  Fly    66 YLPKDKQFLITRNVPCYRRCKQMEYVGE-ETLVEEESGDGGWVETHQLNDDGTTQLEDKICELTM 129
            |||.|||||:|:|||||:|||||||..| |.::||:.||||||:|:  ::.|.|.:.:.:.|:|:
Mouse    66 YLPTDKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTY--HNTGITGITEAVKEITL 128

  Fly   130 EETKEEMHTPDSDKSAPGAGGQAEDEDDDEAIDMDDFEESGMLELVDPAVATTTRKPEPEAKASP 194
             |:|:.:...|.....    .:.::||:.||.||:::||||:|| .|.|...|.:         .
Mouse   129 -ESKDSIKLQDCSALC----DEEDEEDEGEAADMEEYEESGLLE-TDEATLDTRK---------I 178

  Fly   195 VAAASGDAEASG-DSVLHTRTYDLHISYDKYYQTPRLWVVGYDEQRKPLTVEQMYEDVSQDHAKK 258
            |.|....|:|.| |::|.||||||:|:|||||||||||:.||||||:|||||.||||:||||.||
Mouse   179 VEACKAKADAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKK 243

  Fly   259 TVTMESHPHLPGPNMASVHPCRHADIMKKIIQTVEEGGGQLGVHLYLIIFLKFVQTVIPTIEYDF 323
            |||:|:|||||.|.|.||||||||::|||||:||.||||:||||:||:|||||||.||||||||:
Mouse   244 TVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAVIPTIEYDY 308

  Fly   324 TQNFNM 329
            |::|.|
Mouse   309 TRHFTM 314

Known Domains:


GeneSequenceDomainRegion External IDIdentity
Atg3NP_649059.1 Autophagy_N 8..135 CDD:281916 87/128 (68%)
Autophagy_act_C 219..280 CDD:281917 49/61 (80%)
Autophagy_C 301..325 CDD:287367 20/24 (83%)
Atg3NP_080678.1 Autophagy_N 8..133 CDD:281916 86/126 (68%)
Autophagy_act_C 204..265 CDD:281917 47/62 (76%)
Autophagy_C 286..309 CDD:287367 18/23 (78%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 C163185974
eggNOG 1 0.900 E1_KOG2981
Hieranoid 1 1.000
Homologene 1 1.000 H6836
Inparanoid 1 1.050 428 1.000 Inparanoid score I1719
Isobase 00.000 Not matched by this tool.
OMA 1 1.010
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 FOG0004324
OrthoInspector 1 1.000 T1085083
orthoMCL 1 0.900 OOG5_128240
Panther 1 1.100 LDO PTHR12866
Phylome 1 0.910 0.667 Consistency score
RoundUp 1 1.030 avgDist Average_Evolutionary_Distance R108
TreeFam 1 0.960
1312.790

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