DRSC/TRiP Functional Genomics Resources

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Protein Alignment Polr3D and F26E4.4

DIOPT Version :10

Sequence 1:NP_649028.3 Gene:Polr3D / 40002 FlyBaseID:FBgn0036775 Length:415 Species:Drosophila melanogaster
Sequence 2:NP_492595.1 Gene:F26E4.4 / 259393 WormBaseID:WBGene00009159 Length:408 Species:Caenorhabditis elegans


Alignment Length:398 Identity:98/398 - (24%)
Similarity:153/398 - (38%) Gaps:103/398 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    68 PNLNAVRNKNANVKTSKDTTQPRSGRRGGRGNGTGATRGRGGNSAGGG---NSTLIQTQGLFSEG 129
            |||:....:.|..:        :...|||..:..||.||||....|.|   ...||||.|:||||
 Worm     7 PNLSLAGKREAPAQ--------QKNNRGGSTSTRGAGRGRGARGRGAGPRPKQELIQTGGVFSEG 63

  Fly   130 -AGDVHVR---------------RSTGNGTAYARGGEEVSVTRKRVDRKDDKSQAERIKELLGES 178
             .||...|               |..|:|...:..|:     ..:..:|::|:.|       |::
 Worm    64 LGGDFPSRKKDKDSDASQFSYSNREKGSGAPSSSTGD-----HNKEGKKEEKNVA-------GKA 116

  Fly   179 DASGGE---LSEEEANKTEM-ALRPILLKEGLWVTQKTPIAKQEIASSTSTLKDTLAVAQHLQQL 239
            ...|.:   .|::|.:|.|: ||.|......|......|:              .|......|.|
 Worm   117 SFEGWDALWCSDDEGDKEELKALMPPPFISDLRRGNIMPV--------------VLPSEDQPQFL 167

  Fly   240 HVAAQAA--SLEEP---------------PLQYGRYPRTIGNFLDSSEAQIFLMQLPDVLPCVGD 287
            ::..::|  ||||.               |......|..:.|.|::|.:.:..:|||.|:..:.:
 Worm   168 NIINKSARLSLEEDEAPIDEKKPLNTESGPKSRKATPEQLINMLEASSSDLLHLQLPSVIGSICN 232

  Fly   288 DSEDPEPSKGDHQATSE-SEPAS--PADKCSNGPKGSVLRQLEEGQIGKILRYKSGRVKLQLGDT 349
            :.|      .:.:|:.| .||.:  |....|..|..|.|.|  ..:|||:...:.||:.|::|..
 Worm   233 NIE------ANVEASMEVDEPDNDVPTGIVSAPPPPSGLPQ--NRKIGKLQVTRKGRMILKIGGH 289

  Fly   350 RFDLDMGLDPGFLQ--ELMSVTANREQ--------RSGNMIN----LGPIQAKLKATPDWVHLFQ 400
            ..|:......|..|  .|:.|..|.:|        .:..|||    ||.::..|..:..|..|.:
 Worm   290 SIDITSKPTTGKKQGTVLLEVDPNADQLQAPSTFSSAPEMINSLYHLGNVKHNLVGSMTWGALNE 354

  Fly   401 QQDAASKR 408
            :    |||
 Worm   355 K----SKR 358

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Polr3DNP_649028.3 RNA_pol_Rpc4 270..395 CDD:461558 35/141 (25%)
F26E4.4NP_492595.1 RNA_pol_Rpc4 <235..344 CDD:461558 30/116 (26%)

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