Protein Alignment CG7402 and ARSI

DIOPT Version :9

• Sequence 1: NP_649023.1
• Gene: CG7402 / 39994
• FlyBaseID: FBgn0036768
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001012301.1
• Gene: ARSI / 340075
• HGNCID: 32521
• Length: 569
• Species: Homo sapiens
• Alignment Length: 537
• Identity: 184/537 - (34%)
• Similarity: 275/537 - (51%)
• Gaps: 65/537 - (12%)

  Fly    28 PNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVPNLCTPSRATLLTGKYPIHTG 92
            |:|:.||.||.|.:||.:|||: |.||.:|.||..|:.|..:|:..:|||||:.||||:|.||||
Human    47 PHIIFILTDDQGYHDVGYHGSD-IETPTLDRLAAKGVKLENYYIQPICTPSRSQLLTGRYQIHTG 110

  Fly    93 MQHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRKDLTPTMRGFDHHFGYYNGYI 157
            :||.:|...:|..||..:..:|:..::||||||:||||||||:||:..||.||||...|...|.:
Human   111 LQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNV 175

  Fly   158 DYYDHQVRMLDRNYSAGLDFRRDLEPCPEANGTYATEAFTSEAKRIIEQHDKSKPLFMVLSHLAV 222
            |||.:.  ..|.....|.|...........:|.|:|..:...|..|:..|...:|||:.::..||
Human   176 DYYTYD--NCDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHILASHSPQRPLFLYVAFQAV 238

  Fly   223 HTGNEDSPMQAPEEEVAKFPHIRDPKRRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDN 287
            ||     |:|:|.|.:.::..:.:..||.||.|::.:|::|.....|||..|..|||:|:..|||
Human   239 HT-----PLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDN 298

  Fly   288 GAPTIGIHSNAGSNYPYRGQKESPWEGGIRSAGALWSPLLKERGYVSNQAIHAVDWLPTLAGAAG 352
            |..|.    :.|||:|.||:|.:.||||:|..|.:.|||||.:...|...:|..||.|||.|.||
Human   299 GGQTF----SGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTSRALMHITDWYPTLVGLAG 359

  Fly   353 VSLPQDLPLDGINLWPMLSGNEEPKPRT-MIHVLDEVFGYSSYMRDTLKYVNGSSFKGRYDQW-- 414
            .:......|||.::||.:| .....||| ::|.:|.::.::.:          .|.:|.:..|
Human   360 GTTSAADGLDGYDVWPAIS-EGRASPRTEILHNIDPLYNHAQH----------GSLEGGFGIWNT 413

  Fly   415 -------LGELETNEDDP-LGESYEQHVLASDVQSLLGNRGLTKDRIRQMRSEATETCPPIEGQN 471
                   :||.:....|| .|:......||:     ........:|:..:|
Human   414 AVQAAIRVGEWKLLTGDPGYGDWIPPQTLAT-----FPGSWWNLERMASVR-------------- 459

  Fly   472 PLESHFKCEPLKAPCFFDLAKDPCERYNLAQMYPLQLQQLADELEQIRKTAIPSARVPHSDSRAN 536
                       :|...|:::.||.||.:||...|..::.|...|.:..:|||| .|.|..:.||:
Human   460 -----------QAVWLFNISADPYEREDLAGQRPDVVRTLLARLAEYNRTAIP-VRYPAENPRAH 512

  Fly   537 PTFHNGNWEWWNNTDTQ 553
            |.|:.|.|..|.:.:.:
Human   513 PDFNGGAWGPWASDEEE 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	160/441 (36%)
		4-S	28..436	CDD:293753	156/418 (37%)
ARSI	NP_001012301.1	4-S	48..478	CDD:293753	165/482 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	510..539		7/20 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157147
Domainoid	1	1.000	290	1.000	Domainoid score	I1555
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	350	1.000	Inparanoid score	I2283
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D375140at33208
OrthoFinder	1	1.000	-	-		FOG0000852
OrthoInspector	1	1.000	-	-		mtm8485
orthoMCL	1	0.900	-	-		OOG6_100690
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X499
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.660