Protein Alignment ais and Dbp80

DIOPT Version :10

• Sequence 1: NP_649009.1
• Gene: ais / 39979
• FlyBaseID: FBgn0036754
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001263168.1
• Gene: Dbp80 / 3354919
• FlyBaseID: FBgn0024804
• Length: 481
• Species: Drosophila melanogaster
• Alignment Length: 535
• Identity: 143/535 - (26%)
• Similarity: 233/535 - (43%)
• Gaps: 106/535 - (19%)

  Fly    16 FTKKSKKEPSSKQQLQPLPEVSKHEEPVKS-EESDKDDEDITEFRLLDGDSSNQPKRKKPKKEKT 79
            :.||::.:..||.       |.|.....|| ||:|.|..|..|..||         .|...|...
  Fly     4 WAKKAEDQEVSKL-------VDKLNLDSKSGEETDFDVADPAETSLL---------IKILGKGLV 52

  Fly    80 LSPKELEIQKAAEEANETRKQYGIRVLGKNVPPPVDSFGTLTRDFKMLPRLQQNLL----SRNFD 140
            .:...|:||:                  ||...|:.|..|    |:.| .|:.:||    :..|:
  Fly    53 NTKLSLDIQQ------------------KNPNSPLHSVKT----FEAL-HLKASLLKGIYAMGFN 94

  Fly   141 HPTPIQMQALPVLL--QRRALMACAPTGSGKTLAFLTPIINGLRA---HKTTGLRALVLAPTREL 200
            .|:.||..|||.||  ..:.::|.:.:|:|||.||:..:::.:..   |.    :.|.|:||.||
  Fly    95 TPSKIQETALPTLLADPPQNMIAQSQSGTGKTAAFVLAMLSRVNVCLNHP----QVLCLSPTYEL 155

  Fly   201 AQQ---IYRECAELTRETGLRTHFISKVSEAKQKHGAECKQRYDILVSTPNR-----VRFLLQQE 257
            |.|   :.....:..||..||  |..:..|..:..    |....||:.||.:     ::|
  Fly   156 AIQTGEVAARMGQFCREIKLR--FAVRGEEVDRSK----KIEEHILIGTPGKLLDWGIKF----- 209

  Fly   258 PPLLDLSHVEWFVLDEAD-RLMEEGQNNFKEQLDDIYAACSNPTKCVAFFSATYTVPVAKWALRH 321
             .|.|:..:..||||||| .:..:|.:   :|...|:... ||...:.||||||...|..:|...
  Fly   210 -RLFDMKKISVFVLDEADVMIATQGHH---DQCIRIHKML-NPHCQMLFFSATYGKEVMDFARLI 269

  Fly   322 LKNLVRITIGVQNSATETVQQELLFVGSEGGKLVAIRDLVRQGLQPPVLVFVQSKERAKQLFEEL 386
            :.:...|.:..:..:.|.::|..:...:|.||..||:::.........::|..:|..|..|..::
  Fly   270 VADPTIIRLMREEESLENIKQYYVKCKNEEGKYNAIQNIYGCISVGQAIIFCHTKRTAAWLAAKM 334

  Fly   387 LYDGINVDVIHAERSQHQRDNCVKAFREGSIWVLICTELMGRGIDFKGVNLVINYDFP------P 445
            ..||.:|.|:..:.:..||.:.:..||.|...|||.|.::.||||.:.|.:|:|:|.|      .
  Fly   335 TSDGHSVAVLTGDLTVVQRLDVLDRFRSGLEKVLITTNILSRGIDIEQVTIVVNFDLPVDLDGMA 399

  Fly   446 TTISYIHRIGRTGRAGRPGRAITFFTQEDTSNLRGIALI-IKNSGGTVPEYMLQMKKVRKSEAKM 509
            ...:|:||||||||.            |.::..|...:. :|...|.:.      |::.:|.:..
  Fly   400 DCETYLHRIGRTGRF------------EPSALTRNSPIFGVKAESGKIG------KEINRSSSGA 446

  Fly   510 RA---KKPLDREDIS 521
            .:   :.|.::|:||
  Fly   447 ESGSREMPKEKENIS 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ais	NP_649009.1	SrmB	123..538	CDD:440279	117/427 (27%)
Dbp80	NP_001263168.1	DEADc_DDX19_DDX25	80..277	CDD:350721	62/216 (29%)
		SF2_C_DEAD	288..414	CDD:350174	40/125 (32%)