Protein Alignment Crtc and crtc2

DIOPT Version :10

• Sequence 1: NP_001261997.1
• Gene: Crtc / 39970
• FlyBaseID: FBgn0036746
• Length: 889
• Species: Drosophila melanogaster
• Sequence 2: XP_001339876.2
• Gene: crtc2 / 799532
• ZFINID: ZDB-GENE-030131-2214
• Length: 759
• Species: Danio rerio
• Alignment Length: 829
• Identity: 185/829 - (22%)
• Similarity: 249/829 - (30%)
• Gaps: 355/829 - (42%)

  Fly     3 NPRKFSEKIALQKQKQAEGTAEFERIMKEVYATKRDEPPANQKILDGLVGGQEVSQSSPGAGNGT 67
            |||||||||||..|:|||.||.|..:|.::.:.:              |..:.|.|:.
Zfish    27 NPRKFSEKIALHNQRQAEETAAFREVMMDINSIR--------------VEAERVRQTR------- 70

  Fly    68 GGGGSGSGSGASGGGASPDGLGGGGGS-PTAYRESR---------------------GRSVGVGP 110
                              |.:...||| |...:.||                     .|.|...|
Zfish    71 ------------------DPVPYYGGSLPNVNQMSRCSVETQYPSCLTQQLLEADEEYRDVQPSP 117

  Fly   111 MRRPSERKQDRSPYGSSSTQQTLDNGQLNPHLLGPPTAESLWRRS-SSDSALHQSALVAGFNSDV 174
            :.||..|..|.:||.||.              |.||.|.: |||: ||.||..:|.:|
Zfish   118 LSRPYRRHFDSAPYLSSH--------------LSPPRAPA-WRRNWSSCSATEKSQMV------- 160

  Fly   175 NSMGANYQQQQHQQQQQPGQPRSHSPHHGINRTMSPQAQRRKSPLLQPHQLQLQQLQQQQQQMQH 239
                                   ..|...:|||.|..|
Zfish   161 -----------------------RLPLTALNRTNSDSA--------------------------- 175

  Fly   240 QHQLHQQLQMQQLQQHQQQHQQQQQQQNTPYNNAKFTNPVFRPLQDQVNFANTGSLPDLTALQNY 304
               ||..::..||    ..|.:..|..||...:..|..|.  ||
Zfish   176 ---LHTSVRNTQL----HGHLKSTQTLNTQTRHCGFALPA--PL--------------------- 210

  Fly   305 GPQQQQQQSQQQPSQQQQQLQQTLSPVMS-----PHNHRRERDQS------PSPFSPAGGGGGAG 358
             .::..|:..|.|..::      |||:.|     |..|....||.      ||..|.:|
Zfish   211 -IEENIQEETQSPKLKK------LSPMASSGCETPVVHFPSPDQQVSSLPVPSALSTSG------ 262

  Fly   359 PGSPYQQQQHSPT---GNTQQQQQQHQQPSNSPHLSFTNLATTQAAVTTFNP-------LPTLGP 413
             ..|.....|.|:   |..:.:.|           |.|||..:    |:.:|       ||.|..
Zfish   263 -SLPDLSSLHLPSPLPGGLESEPQ-----------SGTNLLNS----TSTHPDIMADFSLPGLSS 311

  Fly   414 HNATDYRQPPNPPSPRSSPGLLSSVSATDLHSSAPASPIRQQQQAHQQQQQQQQAQQQQQQFDNS 478
            ........|....|..|:|.:.|.:|:..|.||..:...|                     ...|
Zfish   312 PLQASLSNPLLQSSSLSNPSIQSCLSSLSLPSSLSSVSSR---------------------LSLS 355

  Fly   479 YNSLNTSFHNQFEIFSLGDSNSSPEQQGFANNFVALDFDDLSGGGGGGPSGGGGSNGGGLTNGYN 543
            .:||.:|..||    ||..|.||   ...:|..|.......|...|.|.||...|
Zfish   356 NSSLQSSLSNQ----SLRSSLSS---SSLSNQSVQSSASRCSISSGIGGSGSCSS---------- 403

  Fly   544 KPEMLDFSELSGSPEASGNNNHMRRGVSNLNNNGLSNGVVGSTHNGSTNLNGAGNNNSSSGGGTA 608
                   |.:||||..:|..:..|..:|.|        :|                 .|.|....
Zfish   404 -------SSVSGSPRVAGGTSRKRAQLSPL--------IV-----------------PSGGESRW 436

  Fly   609 QDP--LGITTSPV--------------------PSPLGCPSSPLPIPIPMSAQSSPQQQHHHHQQ 651
            |.|  ...|.||.                    |....|.....|.| |:|.|  |.:|:.|.:.
Zfish   437 QHPKQFSPTASPTLPSIAQGALLNSCKVHKETKPPAYPCSHHIRPAP-PLSHQ--PLRQYFHPEP 498

  Fly   652 QQQ----------QHHQQQHHQQQQLSLSLHHSPHHSPMH---------SPHHGNSP---LSSSS 694
            |.|          ..|||.|:|:|:          |||:|         .||....|   .:..:
Zfish   499 QYQSIPELEQWIHNEHQQTHNQRQK----------HSPVHKHPQTHAKFEPHLQYPPQQAFTQHA 553

  Fly   695 P----VSHNACSNSNVVMNHQQQQQQHHHQQHHHQGSSQSHTPTTANIP 739
            |    :.|:         :|.|:||...|||:.:| :.|.|..|....|
Zfish   554 PLYPQIQHH---------HHHQEQQNQWHQQNQYQ-NQQLHQNTAIQCP 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Crtc	NP_001261997.1	TORC_N	3..61	CDD:463738	22/57 (39%)
		TORC_C	<761..795	CDD:463740
crtc2	XP_001339876.2	TORC_N	27..81	CDD:463738	26/92 (28%)
		TORC_M	169..301	CDD:463739	42/217 (19%)