Protein Alignment Crtc and Crtc3

DIOPT Version :10

• Sequence 1: NP_001261997.1
• Gene: Crtc / 39970
• FlyBaseID: FBgn0036746
• Length: 889
• Species: Drosophila melanogaster
• Sequence 2: NP_001414170.1
• Gene: Crtc3 / 365297
• RGDID: 1309666
• Length: 618
• Species: Rattus norvegicus
• Alignment Length: 867
• Identity: 183/867 - (21%)
• Similarity: 257/867 - (29%)
• Gaps: 333/867 - (38%)

  Fly     2 ANPRKFSEKIALQKQKQAEGTAEFERIMKEVYATKRDEPPANQKILDGLVGGQ--EVSQSSPGAG 64
            ||||||||||||..|:|||.|..||::|.::..::.......|..|....||.  .|||..
  Rat    10 ANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQRLQQLRLTQHHGGSLPNVSQLR---- 70

  Fly    65 NGTGGGGSGSGSGASGGGASP---------DGLGGGGGSPTAYRESRGRSVGVGPMRRPS----E 116
                             |::|         |.:.|........|.:|.|   ..|:.|.|    .
  Rat    71 -----------------GSAPELQPSLHHADNVRGTRHHGLVERPARNR---FHPLHRRSGDKPG 115

  Fly   117 RKQDRSPYGSSSTQQTLDNGQLNPHLLGPPTAE---------SLWRRSSSDSALHQSALVAGFNS 172
            |:.|.:.:.:|.:.|.||.......   ||..|         |...|::||||||.|||
  Rat   116 RQFDGNAFAASYSSQPLDESWPRQQ---PPWKEEKHPGFRLTSALNRTNSDSALHTSAL------ 171

  Fly   173 DVNSMGANYQQQQHQQQQQP----GQPRSHSPHHGI--------NRTMSPQAQRRKSPLLQPHQL 225
                         ..:.|.|    ||....:|:.|.        .....|...:.::.|..|..|
  Rat   172 -------------STKPQDPYGGGGQSAWPAPYMGFCDGENDGRGEAAFPGLLKEENLLNVPKPL 223

  Fly   226 QLQQLQQQQQQMQHQHQLHQQLQMQQLQQHQQQ----------HQQQQQQQNTPYNNAKFTNPVF 280
                          ..||.:..::|.|....:.          |..|              |...
  Rat   224 --------------PKQLWETKEIQSLSGRPRSCDVGGGSAFPHNGQ--------------NTGL 260

  Fly   281 RPLQDQVNFANTGSLPDLTALQNYGPQQQQQQSQQQPSQQQQQLQQTLSPVMSPHNHRRERDQSP 345
            .|....:|  ..|||||||.|....|                 |..:|             |.|.
  Rat   261 SPFLGTLN--TGGSLPDLTNLHYSAP-----------------LPASL-------------DTSD 293

  Fly   346 SPFSPAGGGGGAGPGSPYQQQQHSPTGNTQQQQQQHQQPSNSPHLSFTNLATTQAAVTTFNPLPT 410
            ..|.....|...|                       ..|:...||...|.:..|
  Rat   294 HLFGSMSVGNSVG-----------------------NLPAAMTHLGIRNSSGLQ----------- 324

  Fly   411 LGPHNATDYRQPPNPPSPRSSPGLLSSVSATDLHSSAPASPIRQQQQAHQQQQQQQQAQQQQQQF 475
                            |.||:|.:.::::...|.||..:.|                    |...
  Rat   325 ----------------SSRSNPSIQATLNKIALSSSLNSHP--------------------QPSV 353

  Fly   476 DNSYNSLNTSFHNQFEIFSLGDSNSSPEQQGFANNFVALDFDDLSGGGGGGPSGGGGSNGGGLTN 540
            .|:     ::.|....:|||    |:|          :|...:||     |||.........||
  Rat   354 ANA-----SALHPSLRLFSL----SNP----------SLSTTNLS-----GPSRRRQPPVSPLT- 393

  Fly   541 GYNKPEMLDFSELSGSPEASGNNNHMRRGVSNLNNNGLSNGVVGSTHNGSTNLNGAGNNNSSSGG 605
                        ||..|||....|......|.||....|..|.
  Rat   394 ------------LSPGPEAHQGFNRQLSATSPLNPYPASQMVT---------------------- 424

  Fly   606 GTAQDPLGITTSPVPSPLGCPSSPLPIPIPMSAQSSPQ---QQHHHHQQQQQQHHQQQHHQQQQL 667
             :.|.||....:...:.:   |.|.|.|.|   |..||   ||.|.|:...||........|...
  Rat   425 -SEQSPLSFLPTDAQAQV---SPPPPYPTP---QELPQPLLQQPHAHEPPAQQPQAAPSLSQSDF 482

  Fly   668 SLSLHHSP-----------HHSPMH-SPHHGNS-PLSSSSPVSHNACSNSNVVMNHQQQQQQHHH 719
            .|......           ...||. ||..... ||               |..:|::.|...|.
  Rat   483 QLLTAQGSSLTNFFRDVGFDQQPMRPSPAFPQQVPL---------------VQQSHREPQDSFHL 532

  Fly   720 QQHHHQG-SSQSHTPTTANIPSIIFSDYSSNADYTREIFDSLDLD----------LGQMDVAGLQ 773
            :.:.:.. .|..:|..|.:..:.:|...|.......|:  |||:|          :..:.:.||.
  Rat   533 RPNPYSNCGSFPNTILTEDTNTSLFKGLSGGLSGMPEV--SLDMDTPFPLEEELQIEPLSLDGLN 595

  Fly   774 MLSDQNPIMIADPNIEDSFRRD 795
            ||||.: :.:.||::|::||.|
  Rat   596 MLSDSS-MGLLDPSVEETFRAD 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Crtc	NP_001261997.1	TORC_N	3..61	CDD:463738	26/59 (44%)
		TORC_C	<761..795	CDD:463740	13/43 (30%)
Crtc3	NP_001414170.1	None