Protein Alignment Crtc and Crtc

DIOPT Version :10

• Sequence 1: NP_001261997.1
• Gene: Crtc / 39970
• FlyBaseID: FBgn0036746
• Length: 889
• Species: Drosophila melanogaster
• Sequence 2: XP_061513701.1
• Gene: Crtc / 1275523
• VectorBaseID: AGAMI1_001903
• Length: 765
• Species: Anopheles gambiae
• Alignment Length: 937
• Identity: 240/937 - (25%)
• Similarity: 326/937 - (34%)
• Gaps: 314/937 - (33%)

  Fly     1 MANPRKFSEKIALQKQKQAEGTAEFERIMKEVYATKRDEPPANQKILDGLVGGQEVSQSSPGAGN 65
            |||||||||||||..|||||.||||||||:||              ||......:.:..||..|.
Mosquito     1 MANPRKFSEKIALHNQKQAEETAEFERIMREV--------------LDVTSKASKSANLSPTTGT 51

  Fly    66 -GTGGGGS---GSGSGASGGGASPDG--------------------LGGGGGSPTAYRESRGRSV 106
             ||..|||   .:.........:.||                    :.....:|:..||||||:.
Mosquito    52 LGTFRGGSLPNVNNENKQYQEKADDGTNLTELKPYTQPETIKVKKEISPKASTPSHTRESRGRTP 116

  Fly   107 GVGPMR-RPSERKQDRSPYGSSSTQQTLDNGQLNPHLLGPPTAESLWRRSSSDSALHQSALVAGF 170
            | |||| |.|.|..|.||||:|:.           ||:  |..||.|.||.||||:|||..
Mosquito   117 G-GPMRNRQSSRNHDTSPYGNSTV-----------HLI--PPMESNWHRSISDSAIHQSLC---- 163

  Fly   171 NSDVNSMGANYQQQQHQQQQQPGQPRSHSPHHGINRTMSPQAQRRKSPLLQPHQLQLQQLQQ-QQ 234
                           ..|||......:|:|     .|:||..||:.|        ..|.:.: ..
Mosquito   164 ---------------QNQQQDATHLTTHTP-----LTLSPTVQRKIS--------NAQHISKVHN 200

  Fly   235 QQMQHQHQLHQQLQMQQLQQHQQQHQQQQQQQNTPYNNAKFTNPVFRPLQDQVNF---------- 289
            ..|.:.|..|          |...|.......|....:.:..:....|....:|.
Mosquito   201 NHMTNNHHNH----------HHHHHHPSNHHDNGSTQDIRSRSSTALPRLPGINIYPSQNHPDSI 255

  Fly   290 -----ANTGSLPDLTAL-----------QNYGPQQQQQQSQQQPSQQQQQLQQTLSPVMSPHNHR 338
                 :|||||||||::           |.|.|..|.......|....   ..:|||..:..||.
Mosquito   256 QIPIPSNTGSLPDLTSVGYPSMYPATLDQEYDPNGQNHSYCPSPLGTS---PSSLSPTSAIQNHH 317

  Fly   339 RERDQSPSPFS-------------PAGGGGGAGPGSPYQQQQHSPTGNTQQQQQQHQQPSNSPHL 390
            .......:.||             ..|||||||.|.......:|..|............|.||..
Mosquito   318 HHPHPRANSFSGGVSSATGGNGSGGGGGGGGAGGGGSSGGSGNSVGGGYPIPTSHSNSGSVSPTG 382

  Fly   391 SFTNLATTQAAVTTFNPLPTLGPHNATDYR-----------QPPNPPSPRSSPGL---------- 434
            |..:.:.:.::|.   |:..:|  ||.::.           :...|.:..|.|.|
Mosquito   383 SGISCSPSASSVA---PIANMG--NAVNHNNGATLNNGIKGKKAKPQTISSQPFLSVPDSNRYSF 442

  Fly   435 LSSVSATDLHSSAPASPIRQQQQAHQQQQQQQQAQQQQQQFDNSYNSLNTSFHNQFEIFS-LGDS 498
            :|.|:.|  :.:.....::||.|.||||.|.|..||||||.......:.|.....::.|: :.|.
Mosquito   443 MSKVNNT--YDTNQQQSVQQQHQQHQQQPQAQSPQQQQQQQAQQQQRIPTLDQISYDSFTQITDG 505

  Fly   499 NSSPEQQ-------GFANNFVALDFDDLSGGGGGGPSGG---------------------GGSNG 535
            .:||.|.       |...|.......|.......|.|.|                     .|||.
Mosquito   506 LASPNQNSPESILYGSHGNMSPQIMSDYRTRPSPGSSPGLALVNNPDSNSSAPCSPVSHTVGSNN 570

  Fly   536 GGLTNGYNKPEM--------------LDFSELSGSPEASGNNNHMRRGVSNLNNNG--LSNGVVG 584
            |...:.|...::              ||::.|                |.:|..:|  |:..|.|
Mosquito   571 GPTYDKYPTSDVYVQNTLPQYLEHITLDWTTL----------------VQSLVESGCTLTAQVQG 619

  Fly   585 STHNGSTNLNGAGNNNSSSGGGTAQDPLGITTSPVPSPLGCPSSPLPIPIPMSAQSSPQQQHHHH 649
            .|...:..:..:|.:.:..   |..:.|||.|                             |..|
Mosquito   620 DTDFTTNQMVFSGFDETYL---TMNNGLGIRT-----------------------------HTGH 652

  Fly   650 QQQQQQHHQQQHHQQQQLSLSLHHSPHHSPMHSPHHGNSPLSSSSPVSHNACSNSNVVMNHQQQQ 714
            .....|.||....|..||:                            |.| |.|        .|.
Mosquito   653 GNGHTQVHQTATQQTNQLN----------------------------SIN-CQN--------MQN 680

  Fly   715 QQHHHQQHHHQGSSQ-----SHT-----PTTANIPSIIFSDYSSNADYTREIFDSLDLDLGQMDV 769
            .|:.:..:.:.|:::     .:|     |.|..||.|:|:|||     ||:.|:: ||.||.||.
Mosquito   681 MQNTNMSNMYNGTTEPLLSLPNTQSLIEPQTPTIPEIVFTDYS-----TRDDFEA-DLGLGHMDF 739

  Fly   770 AGLQMLSDQNPIMIADPNIEDSFRRDL 796
            ..:|||||.:.::  ||..||||||||
Mosquito   740 QSIQMLSDTSTMI--DPMDEDSFRRDL 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Crtc	NP_001261997.1	TORC_N	3..61	CDD:463738	28/57 (49%)
		TORC_C	<761..795	CDD:463740	18/33 (55%)
Crtc	XP_061513701.1	None