Protein Alignment anchor and gpr155b

DIOPT Version :10

• Sequence 1: NP_001261995.1
• Gene: anchor / 39965
• FlyBaseID: FBgn0036741
• Length: 957
• Species: Drosophila melanogaster
• Sequence 2: XP_073809793.1
• Gene: gpr155b / 100005567
• ZFINID: ZDB-GENE-110815-2
• Length: 790
• Species: Danio rerio
• Alignment Length: 889
• Identity: 267/889 - (30%)
• Similarity: 420/889 - (47%)
• Gaps: 187/889 - (21%)

  Fly    45 VSMNNFYPALVQCFGIIICGYIAGRFKIISNAETKGLGTFVGTFALPSLIFLSLVELNWSAVNWS 109
            :|::..:|||::|||||:|||.|||..|||.|:..|||:||..||||:|:|.::|:|.:..|.||
Zfish    23 MSIDKLFPALLECFGIILCGYAAGRSGIISAAQVNGLGSFVSCFALPALLFKNMVQLQFQHVVWS 87

  Fly   110 FLLAMLVSKAVVFFAVLIISLLVARP-LNYARGGLMAIFCTQSNDFAIGYPIVMALYKDVHPEYA 173
            ||.::|::|..||..|.:::||||.| ..|::.||.|||.|||||||:|||||.|||::.|.||.
Zfish    88 FLWSVLIAKVCVFTLVCVLTLLVADPESKYSKAGLFAIFATQSNDFALGYPIVDALYRNSHSEYE 152

  Fly   174 SYLYLMAPISLAILNPVGLVLMEISKIIKNKEDVTRNPPLCPETCPAEQMSKRNRCLGERSILVF 238
            .|:||:||:||.:|||||..|.||.: .::..|              ...||.:        ::|
Zfish   153 QYIYLVAPVSLMLLNPVGFALCEIQR-WRHSSD--------------PNYSKLH--------VIF 194

  Fly   239 NTLIALFFNPLLLMTLLGVAGGFLFPNGLPEMVSSTLRVLGQSFSATALFLLGLKIVGGTGSERK 303
            ...:.:..||::.|.::|:...|:|...:|.::...:..|..||...|||.|||.:||......:
Zfish   195 TVTLQVLKNPIVFMVMVGIVSHFVFGGRVPVLLGEFVDGLADSFGGAALFYLGLNMVGQMSKLTR 259

  Fly   304 SIGFLLPGVLILVKILVLPLVIRQTVNIMQSGQNFN-DTTELSTFGFLYGTFPAAPGAFVIATQY 367
            |.|..|. :||..|:||:||:.|..|.::.:|.:.: :.:.||.:.||||.||.||...:.|.||
Zfish   260 STGVSLI-LLITAKLLVMPLMCRDMVELLDAGNSSSANHSSLSDYAFLYGVFPTAPSVAIYAAQY 323

  Fly   368 NMEVELVARSMVFCTFISAPLMFISAKMISLTNLKPLDYLHELDAFSFDISVAGAAACCIMLALL 432
            |||:|:|...||..||:|||:|::||.::::..::....:.||...||:||:....|....||::
Zfish   324 NMELEVVTSGMVISTFLSAPIMYVSAWLLTIPWMEASFLVKELQDVSFNISIVCLIALVWTLAVM 388

  Fly   433 IVTKRFKRMPQRITFCLVLSQLMCCIGVILWSKMEHVHRWPLYLQFLLFNI---GTYSTRLWTGL 494
            :::|:|:|||......|.|:||:.|:.::.|..:  :.:..::.|.|.|.:   ..|||.:||||
Zfish   389 LLSKKFRRMPHMFATNLFLAQLLACMSMLFWKFV--LKQGSVFGQILTFTLLYGSLYSTYVWTGL 451

  Fly   495 LAISLLFLQCRSLCFVLKLWPYM-LVFAWGVPAVLSALLIAFDSNVMSGEKHNPSFQYGNAQAAI 558
            ||.||..|....   .||:.|.: ::|.||:|.:....|:.....:  .:..:|:|.||:.|...
Zfish   452 LAFSLTLLGRNE---NLKVKPIVFIIFGWGIPFLTVGGLLMIGQRM--SDSLDPAFFYGSGQIVS 511

  Fly   559 SVFMLVMCFIVTVGCLVL---------HQRYKKRYEKYMT----YSRELSNPESESSDLHSTIST 610
            :|  :|:.|.:.:|.|.|         .|.|:...:..:|    .||.|......|||:..|.:.
Zfish   512 TV--VVLGFSIVLGGLSLMGLSRGAQEEQSYQALDQNSITGASENSRHLQTENQNSSDVDQTHTN 574

  Fly   611 TNLLSHTDQSSIRQSVRTASYSSSSDDEEMIPTAAGLPTSRSNGAASGGAGSGGGGCGSGNGTCC 675
            |::                                                            ||
Zfish   575 TDV------------------------------------------------------------CC 579

  Fly   676 SGGAPVSNSSTTSTVVVDIEDLLNRTRQRASGANNKDLNKIESAPATEEIRNQMCSSSFNCGPST 740
            |...|               |::              ...:..:|..        |:....|.|:
Zfish   580 SEPMP---------------DMI--------------AGHLNDSPVP--------SAGIVLGESS 607

  Fly   741 SRQSCQTIIERYEDQNRRGLEPLEHPSDADEHQTLKHTVLLITLLCSMFVGLAVSIWTLVMEGMS 805
            |....|                       :|.|..:|.:|.:.|:.||...|:..:|.|......
Zfish   608 SSLRVQ-----------------------EERQIARHVLLCLLLIVSMLANLSSCLWWLFSADPG 649

  Fly   806 GIYLELSFLDAFLNFGQGLIVLAVFITDIGELLMPVVKLWRKLWYGANVVSLPHWSNVRP----- 865
            .:||||.|..|..|:|||.:...:|..|...:::|    :||..  |.:.......|:.|
Zfish   650 RLYLELQFFCAVANYGQGFVSFGIFGLDEHLIILP----FRKRL--AALCGFSQEENLEPSAVPE 708

  Fly   866 ETKHICEQFRNHHLENCKKDIAKDRRWRIRVYRRVFYGTEFVSW 909
            |.:..|.||..:|.:.|.:||.::|..|    ..:.||..||.:
Zfish   709 EIRLTCTQFVRYHKDQCVQDIVRNRGMR----APIAYGPTFVDY 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
anchor	NP_001261995.1	YfdV	47..391	CDD:440443	146/345 (42%)
		7tm_GPCRs	429..>536	CDD:475119	36/110 (33%)
		TM helix 2	442..460	CDD:410628	6/17 (35%)
		TM helix 3	475..497	CDD:410628	11/24 (46%)
		TM helix 4	516..532	CDD:410628	4/16 (25%)
		DEP_GPR155	871..953	CDD:239890	13/39 (33%)
gpr155b	XP_073809793.1	None