Protein Alignment: Vps60 and CHMP5

• Sequence 1: NP_001261994.1
• Gene: Vps60
• FlyBaseID: FBgn0036740
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_057494.3
• Gene: CHMP5
• HGNCID: 26942
• Length: 219
• Species: Homo sapiens
• Alignment Length: 222
• Identity: 140/223 (63%)
• Similarity: 171/223 (77%)
• Gaps: 3/223 (1%)

  Fly     1 MNRLFGRGKPKEPGPSLNDCIAGVDARATNIEEKISNLEAELRKYREQMSKMREGPAKNSVKQKA 65
            ||||||:.|||.|.|||.|||..||:||.:|::|||.|:|||.||::|:.|||||||||.|||||
Human     1 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKA 65

  Fly    66 LRVLKQKKAYEQQAESLRNQSFNMEQANYAAQSLKDTQATVAAMKDGVKQMKTEYKKINIDQIED 130
            |||||||:.||||.::|..||||||||||..||||||:.||.|||.|||:||..||::.||||||
Human    66 LRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIED 130

  Fly   131 IQDDMADMFEQADEVQEALGRTYGMPEVDDDDLQAELDALGDEIALDDDTSYLDDVVKAPEAPSR 195
            :||.:.||.|.|:|:||||.|:||.||:|:|||:|||||||||:..|:|:||||:...||..|.
Human   131 LQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYLDEAASAPAIPE- 194

  Fly   196 EPGADSIVPGKSTIETDEFGLPKIPTS 222
              |..:....|..:..||||||:||.|
Human   195 --GVPTDTKNKDGVLVDEFGLPQIPAS 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps60	NP_001261994.1	Snf7	1..190	CDD:304451	127/189 (67%)
CHMP5	NP_057494.3	Snf7	1..201	CDD:328813	130/203 (64%)
		Interaction with VTA1	121..158		23/37 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C273815426
eggNOG	1	0.900				E1_KOG1655
Hieranoid	1	1.000
Homologene	1	1.000				H5757
Inparanoid	1	1.050	282	1.000	Inparanoid score	I2835
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D1301560at2759
OrthoFinder	1	1.000				FOG0003082
OrthoInspector	1	1.000				T1074965
orthoMCL	1	0.900				OOG5_128328
Panther	1	1.100			LDO	PTHR22761
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R2003
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	14	13.800