DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vps60 and Chmp5

DIOPT Version :9

Sequence 1:	NP_001261994.1	Gene:	Vps60 / 39964	FlyBaseID:	FBgn0036740	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_001020581.1	Gene:	Chmp5 / 297995	RGDID:	1305968	Length:	219	Species:	Rattus norvegicus

Alignment Length:	222	Identity:	140/222 - (63%)
Similarity:	171/222 - (77%)	Gaps:	3/222 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNRLFGRGKPKEPGPSLNDCIAGVDARATNIEEKISNLEAELRKYREQMSKMREGPAKNSVKQKA 65
            |||.||:.|||.|.|||.|||..||:||.:|::|||.|:|||.||::|:.|||||||||.|||||
  Rat     1 MNRFFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKA 65

  Fly    66 LRVLKQKKAYEQQAESLRNQSFNMEQANYAAQSLKDTQATVAAMKDGVKQMKTEYKKINIDQIED 130
            |||||||:.||||.::|..||||||||||..||||||:.||.|||.|||:||..||::.||||||
  Rat    66 LRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKEVKIDQIED 130

  Fly   131 IQDDMADMFEQADEVQEALGRTYGMPEVDDDDLQAELDALGDEIALDDDTSYLDDVVKAPEAPSR 195
            :||.:.||.|.|:|:||||||:||.||:|:|||:|||||||||:..|:|:||||:...||..|.
  Rat   131 LQDQLEDMMEDANEIQEALGRSYGTPELDEDDLEAELDALGDELLADEDSSYLDEAASAPAIPE- 194

  Fly   196 EPGADSIVPGKSTIETDEFGLPKIPTS 222
              |..:....|..:..||||||:||.|
  Rat   195 --GVPTDTKNKDGVLVDEFGLPQIPAS 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps60	NP_001261994.1	Snf7	1..190	CDD:304451	126/188 (67%)
Chmp5	NP_001020581.1	Snf7	1..201	CDD:419749	130/202 (64%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21		13/19 (68%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	188..219		13/33 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341716
Domainoid	1	1.000	250	1.000	Domainoid score	I2053
eggNOG	1	0.900	-	-		E1_KOG1655
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5757
Inparanoid	1	1.050	284	1.000	Inparanoid score	I2789
OMA	1	1.010	-	-		QHG53573
OrthoDB	1	1.010	-	-		D1301560at2759
OrthoFinder	1	1.000	-	-		FOG0003367
OrthoInspector	1	1.000	-	-		oto95995
orthoMCL	1	0.900	-	-		OOG6_102352
Panther	1	1.100	-	-	LDO	PTHR22761
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3249
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770