DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vps60 and vps-60

DIOPT Version :9

Sequence 1:	NP_001261994.1	Gene:	Vps60 / 39964	FlyBaseID:	FBgn0036740	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_505219.1	Gene:	vps-60 / 179242	WormBaseID:	WBGene00018290	Length:	217	Species:	Caenorhabditis elegans

Alignment Length:	221	Identity:	122/221 - (55%)
Similarity:	164/221 - (74%)	Gaps:	6/221 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNRLFGRGKPKEPGPSLNDCIAGVDARATNIEEKISNLEAELRKYREQMSKMREGPAKNSVKQKA 65
            |||:||.|| |.|.|.||:.|:.|::|:.:|::||..|:.:|.|.|:|||||||||:||.:||||
Worm     1 MNRIFGTGK-KVPPPDLNNAISNVESRSDSIDKKIQKLDQDLMKLRDQMSKMREGPSKNLIKQKA 64

  Fly    66 LRVLKQKKAYEQQAESLRNQSFNMEQANYAAQSLKDTQATVAAMKDGVKQMKTEYKKINIDQIED 130
            |||||||:.||.|...|..|:|||:|:|:|.|.:||.|.||||||||:|.|:.||||:|||||||
Worm    65 LRVLKQKRMYENQKGQLDQQAFNMDQSNFAIQGMKDNQVTVAAMKDGLKTMQKEYKKMNIDQIED 129

  Fly   131 IQDDMADMFEQADEVQEALGRTYGMPEVDDDDLQAELDALGDEIAL-DDDTSYLDDVVKAPEAPS 194
            :||.|.||.:..:|:|||:.|.|..|::|:.||:|||..||||:.: :.||:|||:.:.||..||
Worm   130 LQDQMEDMLDMNNEIQEAMSRQYDTPDIDEADLEAELAMLGDELDIGESDTNYLDEALAAPTVPS 194

  Fly   195 REPGADSIVPGKSTIETDEFGLPKIP 220
            .:| ...:..|   :|.|||||||:|
Worm   195 DKP-KTRVAEG---LEVDEFGLPKLP 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps60	NP_001261994.1	Snf7	1..190	CDD:304451	107/189 (57%)
vps-60	NP_505219.1	Snf7	1..191	CDD:304451	108/190 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159811
Domainoid	1	1.000	215	1.000	Domainoid score	I1573
eggNOG	1	0.900	-	-		E1_KOG1655
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5757
Inparanoid	1	1.050	243	1.000	Inparanoid score	I2083
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53573
OrthoDB	1	1.010	-	-		D1301560at2759
OrthoFinder	1	1.000	-	-		FOG0003367
OrthoInspector	1	1.000	-	-		oto18249
orthoMCL	1	0.900	-	-		OOG6_102352
Panther	1	1.100	-	-	LDO	PTHR22761
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2003
SonicParanoid	1	1.000	-	-		X3249
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800