Protein Alignment Eip74EF and ETV5

DIOPT Version :10

• Sequence 1: NP_730288.1
• Gene: Eip74EF / 39962
• FlyBaseID: FBgn0000567
• Length: 883
• Species: Drosophila melanogaster
• Sequence 2: NP_004445.1
• Gene: ETV5 / 2119
• HGNCID: 3494
• Length: 510
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 98/353 - (27%)
• Similarity: 138/353 - (39%)
• Gaps: 58/353 - (16%)

  Fly   558 NYYGSSGAGSGGTQPGGPGNPQTPGYLTTSYFN---APTAATAAASQRGTTINGYHSLHQQQQQQ 619
            ||.........|.:|..|  |.||  |:.::.|   .|..||...|...........:.......
Human   119 NYCAYDRKPPSGFKPLTP--PTTP--LSPTHQNPLFPPPQATLPTSGHAPAAGPVQGVGPAPAPH 179

  Fly   620 QQSQQSQQQQQLA-----HQQLSHQQQQALHQQLSHQQQQQQQQQQQHPHSQLNGPHPHSHPHSH 679
            ...:...|||..|     ||.|...:....:|..|.|:.|:|..:..||..    |.|.....:.
Human   180 SLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFP----PQPGVPGDNR 240

  Fly   680 PHSHPHAGQHTHSTIAAAAAAAAASVVSSSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQPAT 744
            |..|    :.....|..||..............:....:.......|....:..|..|   :|..
Human   241 PSYH----RQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPAHGFQSPMGIKQ---EPRD 298

  Fly   745 SSVSYDL-----SYMLELGGFQQRK------AKKPR---------KPKLEMGVKRRS---REG-- 784
            ..|..::     |||  .||:....      .|.||         ..:||..||:..   |||
Human   299 YCVDSEVPNCQSSYM--RGGYFSSSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGPP 361

  Fly   785 ----STTYLWEFLLKLLQDREYCPRFIKWTNREKGV-FKLVDSKAVSRLWGMHKNKPDMNYETMG 844
                .:..||:||:.||.|.... .||.||.|  |: |||::.:.|:|.||:.||:|.|||:.:.
Human   362 YQRRGSLQLWQFLVTLLDDPANA-HFIAWTGR--GMEFKLIEPEEVARRWGIQKNRPAMNYDKLS 423

  Fly   845 RALRYYYQRGILAKVDGQRLVYQFVDVP 872
            |:|||||::||:.||.|:|.||:||..|
Human   424 RSLRYYYEKGIMQKVAGERYVYKFVCDP 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_730288.1	ETS	786..872	CDD:197710	42/86 (49%)
ETV5	NP_004445.1	ETS_PEA3_N	1..366	CDD:461371	55/263 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..208		18/80 (23%)
		ETS	367..452	CDD:197710	43/88 (49%)