Protein Alignment CG12229 and pkmb

DIOPT Version :10

• Sequence 1: NP_648980.1
• Gene: CG12229 / 39945
• FlyBaseID: FBgn0036723
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: XP_005163170.4
• Gene: pkmb / 445094
• ZFINID: ZDB-GENE-040801-230
• Length: 586
• Species: Danio rerio
• Alignment Length: 538
• Identity: 111/538 - (20%)
• Similarity: 194/538 - (36%)
• Gaps: 160/538 - (29%)

  Fly    88 DELRRML-----------ENGTYTFHVDTVGNKPDELKAI----LDTMNIAISAHSAERELRLTT 137
            :.||.|:           .:||:.:|.:|:.:..:.:::.    :|...:||
Zfish   114 ETLREMILSGMNVARLNFSHGTHEYHAETIKSVREAIESFGAGTIDYRPVAI------------- 165

  Fly   138 GLALEINGECCRVGRLRNNCT--VMLARGGVVTLTTDESYR--------YKGFKEIVYVINLRCY 192
              ||:..|...|.|.::.:.|  |.|.:|.::.||.|:.:.        :..:|.|..|
Zfish   166 --ALDTKGPEIRTGLIKGSGTEEVKLVKGNIIKLTLDDKFMDNCDENTLWLDYKNITKV------ 222

  Fly   193 LASVQLGDIVMIGREVRGKVVKTL-REALTVMIIDAGLVASYDFIELPRQCHALDPDLYPDLYMK 256
               ||.|..:.:...:....||.: .:.|...|.:.|::.|...:.||..  .:|.....:..:|
Zfish   223 ---VQQGSHIYVDDGLISLKVKEIGSDFLNCEIENGGMLGSKKGVNLPGA--NVDLPAVSEKDIK 282

  Fly   257 DLEMAASLNANYVVLPKIRCKSFLRAVRQTL-NSDFNLKLIGMID-FEYVRSNMLDLLGIIKLVD 319
            ||:.......:.|....||..:.:.|||:.| ....::::|..:: .|.||.  .|  .|::..|
Zfish   283 DLQFGVEQGVDMVFASFIRKAADVHAVRKVLGEKGKDIRIISKLENHEGVRK--FD--EILEASD 343

  Fly   320 YIWIP--DMFNVNCCVYNYIMEDVLPISQCQK--KPVI-GTVPLERCSDFK-----RFELHD--- 371
            .|.:.  |: .:........:...:.||:|.:  ||:| .|..||  |..|     |.|..|
Zfish   344 GIMVARGDL-GIEIPTEKVFLAQKMMISRCNRIGKPIICATQMLE--SMIKKPRPTRAESSDVAN 405

  Fly   372 -FLWKVDAIHIQKSPWCNKYPL---IVKKLM--------------------------PIKDYRVG 406
             .|...|.|.:.......:||:   :.:.|:                          |.:...||
Zfish   406 AVLDGADCIMLSGETAKGEYPIESVLTQHLIAREAEAAMFHRQLFEELRRTSHLTRDPTESVAVG 470

  Fly   407 AVQNKMVLKSILTSYQTIVNFIIRTISSIEC--QAIFLFTTCETASVALSRIEIYCPVYVMVPLE 469
            ||:                       :|.:|  .||...|....::..|||.....|:.
Zfish   471 AVE-----------------------ASFKCCASAIICLTKTGRSAQLLSRYRPRAPIM------ 506

  Fly   470 ETDDAETITCKVELARALHLRRNMHPVLYTKDLNECSYSPIEFGVDFMRKKGCLEVGDFVVTLEV 534
                  .:|...:.:|.|||.|.:.|:||||..|:.....::..|.|              .||:
Zfish   507 ------AVTRNGQTSRQLHLYRGVIPILYTKPANDIWAEDVDLRVSF--------------ALEI 551

  Fly   535 GKEDK-----DNVVIGIG 547
            ||..|     |.:::..|
Zfish   552 GKHRKYFKSGDVIIVVTG 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12229	NP_648980.1	Pyruvate_Kinase	126..530	CDD:453956	94/461 (20%)
pkmb	XP_005163170.4	None