Protein Alignment CG12229 and pkma

DIOPT Version :10

• Sequence 1: NP_648980.1
• Gene: CG12229 / 39945
• FlyBaseID: FBgn0036723
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: XP_073785020.1
• Gene: pkma / 335817
• ZFINID: ZDB-GENE-031201-4
• Length: 555
• Species: Danio rerio
• Alignment Length: 522
• Identity: 112/522 - (21%)
• Similarity: 190/522 - (36%)
• Gaps: 145/522 - (27%)

  Fly    88 DELRRMLE-----------NGTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRLTTGLAL 141
            |.|:.|::           :|::.:|.:|:.|          ......|......:.| ..|:||
Zfish    83 DTLKEMIKSGMNIARMNFSHGSHEYHGETIKN----------VREACASFEPGSIQYR-PVGIAL 136

  Fly   142 EINGECCRVGRLRNNCT--VMLARGGVVTLTTDESYR-----------YKGFKEIVYVINLRCY- 192
            :..|...|.|.::.:.|  |.|.:|..:.:|.|:|:.           ||...::|.| ..:.|
Zfish   137 DTKGPEIRTGLIKGSGTAEVELKKGNKIKVTLDDSFMENCDEDTLWLDYKNITKVVEV-GSKVYI 200

  Fly   193 ---LASVQLGDIVMIGREVRGKVVKTLREALTVMIIDAGLVASYDFIELPRQCHALDPDLYPDLY 254
               |.|:|   ::.||.:.           |...|.:.|.:.|...:.||..  |:|.....:..
Zfish   201 DDGLISLQ---VLQIGSDY-----------LICEIENGGSLGSKKGVNLPGA--AVDLPAVSEKD 249

  Fly   255 MKDLEMAASLNANYVVLPKIRCKSFLRAVRQTL-NSDFNLKLIGMID-FEYVRSNMLDLLGIIKL 317
            :|||:....:..:.:....||..:.::|||:.| ....|:|:|..:: .|.||  ..|  .|::.
Zfish   250 IKDLQFGVEMGVDMIFASFIRKAADVQAVRKVLGEKGKNIKIISKLENHEGVR--RFD--EIMEA 310

  Fly   318 VDYIWIP--DMFNVNCCVYNYIMEDVLPISQCQK--KPVI-GTVPLERCSDFK-----RFELHD- 371
            .|.|.:.  |: .:........:...:.|.:|.|  ||:| .|..||  |..|     |.|..|
Zfish   311 SDGIMVARGDL-GIEIPTEKVFLAQKMMIGRCNKAGKPIICATQMLE--SMIKKPRPTRAEGSDV 372

  Fly   372 ---FLWKVDAIHIQKSPWCNKYPL------------------------IVKKLMPI-----KDYR 404
               .|...|.|.:........|||                        .:::.:|:     :...
Zfish   373 ANAVLDGADCIMLSGETAKGDYPLEAVRTQHMIAREAEAAMFHRQVFEDLRRCLPLSTDPAEAIA 437

  Fly   405 VGAVQNKMVLKSILTSYQTIVNFIIRTISSIECQAIFLFTTCETASVALSRIEIYCPVYVMVPLE 469
            :|||:...   .||:|     .||:.|.|......|             ||.....|:..:...|
Zfish   438 IGAVEASF---KILSS-----AFIVLTGSGRSAHLI-------------SRYRPRAPILAVTRNE 481

  Fly   470 ETDDAETITCKVELARALHLRRNMHPVLYTKDLNECSYSPIE----FGVDFMRKKGCLEVGDFVV 530
            :|            ||..||.|.:.|:.|....|:.....::    |.:|..:.:|..:.||.|:
Zfish   482 QT------------ARQAHLYRGIFPIYYNSPSNDVWAEDVDLRVNFAMDVGKARGFFKAGDVVI 534

  Fly   531 TL 532
            .|
Zfish   535 VL 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12229	NP_648980.1	Pyruvate_Kinase	126..530	CDD:453956	102/469 (22%)
pkma	XP_073785020.1	None