Protein Alignment CG12229 and CG2964

DIOPT Version :10

• Sequence 1: NP_648980.1
• Gene: CG12229 / 39945
• FlyBaseID: FBgn0036723
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: NP_608713.2
• Gene: CG2964 / 33475
• FlyBaseID: FBgn0031462
• Length: 554
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 109/540 - (20%)
• Similarity: 207/540 - (38%)
• Gaps: 99/540 - (18%)

  Fly    75 LGLVAKL-VTETTHDELRRMLENGTYTFHVDTVGNKPDELKAILDTMNIAIS-AHSAERELRLTT 137
            :.|:|.: |:....|.:..|:..|...|.::......:.....::.:|.|:. .|....::| |.
  Fly    34 VSLIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTIELINEALERIHKETGQIR-TV 97

  Fly   138 GLALEINGECCRVGRLRNNCTVMLARGGVVTLTTDESYRYKGFKEIVYV-----INLRCYLASVQ 197
            .:|.:..|...|.|.|..:  |.|..|..:.|:.:.....||.||.|||     |||      .:
  Fly    98 AIAADTRGPQIRTGLLDGD--VFLRSGDNLRLSINRDLYDKGNKEAVYVDYPNIINL------TK 154

  Fly   198 LGDIVMI--GREVRGKVVKTLREALTVMIIDAGLVASYDFIELPRQCHALDPDLYPDL------Y 254
            .||.:.|  ||.:. .:::...:.|...:|..|        :|...|:.:.|::..||      .
  Fly   155 TGDRLFIDDGRLLL-HILEVGVDGLLCEVIHGG--------QLNNNCNVILPEIEIDLPAVSEKD 210

  Fly   255 MKDLEMAASLNANYVVLPKIRCKSFLRAVRQTL-NSDFNLKLIGMIDFEYVRSNMLDLL----GI 314
            |.|::.:...|.:::....:|....::.:|..| ....::|:|..:|.:...|...::|    |:
  Fly   211 MFDIQFSIKANVDFLFASAVRSAKNVKELRTVLGEKGKHIKIIAKMDSKIALSRFSEILRAADGL 275

  Fly   315 I----KLVDYIWIPDMFNVNCCVYNYIMEDVLPISQCQK--KPVI---------GTVP---LERC 361
            :    .|...|.|..:|.....:          :.||.|  ||||         .|:|   ...|
  Fly   276 LLSRADLGTQIPIEKLFITQKSI----------LGQCNKVGKPVIVASHILESMRTLPHPTRAEC 330

  Fly   362 SDFKR--FELHDFLWKVDAIHIQKSP-----WCNKYPLIVKKLMPIKDYRVGAVQNKMVLKSILT 419
            .|...  .:..|.:.....:.|...|     .|:......:|::..:|.....|..   ::..|.
  Fly   331 FDLANAIIDGADCIMLSSEVAIGSFPKETVATCDTLCREAEKVLWFRDLFSDLVSE---VRGELD 392

  Fly   420 SYQTIVNFIIRTISSIECQAIFLFTTCETASVALSRIEIYCPVYVMVPLEETDDAETITCKVELA 484
            :..::....:.|........|.:.||...::..:|:....||:..:...|.|            |
  Fly   393 AAHSLAIAAVETAKRTNATLIIVLTTSGRSATLVSKFRPRCPIMAITRCERT------------A 445

  Fly   485 RALHLRRNMHPVLYTKDLNECSYSP-----IEFGVDFMRKKGCLEVGDFVVTLEVGKEDKDNVVI 544
            |.::|.|.:.|:|||.: ....|:.     ::|.:...:|.|.::.||.:|.:...|:..
  Fly   446 RWVYLHRGVLPILYTLE-PSTDYATDVDARVQFAMTSAKKWGIIDDGDPIVIVSAWKDGG----- 504

  Fly   545 GIGEDVCILRAFYVSPLFAC 564
            |...:|.::.||:.:....|
  Fly   505 GFTNNVRVVYAFFEADRVDC 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12229	NP_648980.1	Pyruvate_Kinase	126..530	CDD:453956	93/451 (21%)
CG2964	NP_608713.2	Pyruvate_Kinase	32..515	CDD:453956	106/529 (20%)