Protein Alignment CG6652 and Lca5l

DIOPT Version :10

• Sequence 1: NP_648946.3
• Gene: CG6652 / 39905
• FlyBaseID: FBgn0036687
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001402657.1
• Gene: Lca5l / 498065
• RGDID: 1562512
• Length: 734
• Species: Rattus norvegicus
• Alignment Length: 589
• Identity: 130/589 - (22%)
• Similarity: 236/589 - (40%)
• Gaps: 94/589 - (15%)

  Fly    15 VSQSEPNNLMAASAKSCESLFSASSRESASLIYQRSKPPPPQ-------QRGGVKGSGSMSSQ-- 70
            ||:.:|..|:              .:|.....|...|.|.|:       ::..:..:...|||
  Rat    85 VSRHQPEQLL--------------GKEKEKRKYNTCKFPQPKGQKDIPAEKRHIWNASFFSSQIQ 135

  Fly    71 ----NHSEIHQRVMSARNLRAKTFQNQLADAQAEIANLAHENRMLRTLHNRQSSALNKYEAHNAE 131
                ....:..|::|||..:.|..:|:|||...::.....||:.|:.|..|...|:..|......
  Rat   136 TIAKRRDTMTHRILSARLHKIKELKNELADIHRKLEATILENQFLKQLQLRHLKAIGTYVNSQNN 200

  Fly   132 LPKLLSSHAEELRMWQTKYRKLQAANKALELKLKQKEEIILTLSDQNKHYSQLNKDKNLDERQKL 196
            ||::...|..|::..:...||.|...:|:..||::.:..:|...|..:...:|::||||.||::|
  Rat   201 LPQITVKHQNEVKNLRQLLRKSQEKERAVSRKLRETDSELLRTKDALQALQRLSEDKNLAEREEL 265

  Fly   197 QEKLKSLEQRLEEKDNDMKLMARKVQLESKNIRQQLLNEQRKGKEVMLKLEKAKLEISGY----- 256
            ..:|..|..::|..|..::.:.::::|.:::..:||..|.||........:..:.|:...
  Rat   266 THRLTDLTAKMEANDKKIQNLEKQLRLNNRSFSRQLAKENRKTLAAQTATKALQAEVRQLQQKLK 330

  Fly   257 ---RKLEEYTLGTDKVNPLSSGRRTKLSGVTDEPD--KIDKLEKSMEMLDKAIE-KNNQSEFTAL 315
               |:||...:.|:::          |..:.|:.|  |:.. .||::...|::. .|.:.:.|..
  Rat   331 EKDRELEIKNIYTNRI----------LKNLHDKEDYPKVSS-TKSVQADRKSLPFVNVRHQETQK 384

  Fly   316 TDVMESESFYDFEKDSAEDKSGPNTPPSQIERQVGGRGGKLILPPATNHAKMGQKANRSTLSQVL 380
            :||    .|:..:...|:.........::|...:.....||   |....:|...:||.:.|..:.
  Rat   385 SDV----PFWITKDKKAKGNIVHKEKSTEINHDISYHVRKL---PRQEESKRKCEANLTVLKNMP 442

  Fly   381 SAQGKISVSSGKSAKSRIAVAVPKMES-VQVSKRREPETVSRLASAET--KPKQKPLEYE---YE 439
            |.:    ||..:.|..:|.....:..| .|....:|.|......|.||  :||::..:.|   ..
  Rat   443 SPR----VSWEQVATEQICAFHLECHSCTQTDLSKEVEHPKPQTSLETPRRPKERKEDQEKRAIP 503

  Fly   440 DDYEPAG------EDGDDDAYGMMSKMCEGEEPQDNSEENANESSLLKYSAYMDNKSSEG---DP 495
            ::.||..      ||.:|.|  :....|:..:..|..:  |.::         |:.|..|   |.
  Rat   504 EEAEPTAKGSEVPEDAEDKA--LARAACDVGDAGDAGD--AGDA---------DHASDAGDVRDV 555

  Fly   496 LEES----MEEYDGTD--GQQSQGSDDEDISVRAPRLKENMSSLRKQISNDFKERESFLKTFCRQ 554
            :|:|    ..|..|.:  |:....|:..|:.....|.|...|......:...:.....|.|.|||
  Rat   556 VEDSEVIGAHELPGANQAGEVHGASEAGDVEPGRGRRKTPRSRKHYSFTEATENLHHGLPTSCRQ 620

  Fly   555 ASNS 558
            ||.|
  Rat   621 ASGS 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6652	NP_648946.3	Lebercilin	75..261	CDD:464776	49/193 (25%)
Lca5l	NP_001402657.1	Lebercilin	144..336	CDD:464776	48/191 (25%)
		PTZ00121	<207..522	CDD:173412	73/336 (22%)
		PHA03307	464..>733	CDD:223039	41/174 (24%)