DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Exn and si:dkey-172h23.2

DIOPT Version :9

Sequence 1:	NP_001097630.2	Gene:	Exn / 39900	FlyBaseID:	FBgn0261547	Length:	2029	Species:	Drosophila melanogaster
Sequence 2:	NP_957093.1	Gene:	si:dkey-172h23.2 / 393772	ZFINID:	ZDB-GENE-141212-258	Length:	221	Species:	Danio rerio

Alignment Length:	170	Identity:	37/170 - (21%)
Similarity:	57/170 - (33%)	Gaps:	47/170 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1302 LSSLAPTRS-------TFYVEDPEGSLPALPLEP-----------------EIHGSGELDSG-FS 1341
            |.::.|..:       |.:...|:|.:.:|..||                 .:..:|.|:.. ..
Zfish    58 LQAVCPAHNCCESVLVTLFSTGPDGLVHSLATEPLVFVQDLAFDMAQFLVSAVGQTGILEEALLL 122

  Fly  1342 DKNCTPLPETPKFSTVARKAKKEAKANRRRTTIGLRPNDPPPPPPPMTGNKSPLDPEREL---DA 1403
            |::..||.|..|.......|.|....               ||...:.||.:.:||:..|   .|
Zfish   123 DEHQIPLQECEKLDLSLSLALKHLTL---------------PPGWSLIGNNTRMDPQETLLHFAA 172

  Fly  1404 EQTTSWYAECGVFKQATNGAVSPR---GDEPVTPTPS-GH 1439
            .:..|..|...:.:.....|:|.|   ||.||....| ||
Zfish   173 RRGLSKVARFLLKQPGAREALSLRNRQGDTPVLIAQSRGH 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Exn	NP_001097630.2	RhoGEF	1581..1763	CDD:279015
		PH_ephexin	1805..1931	CDD:269929
		SH3_ephexin1_like	1944..1998	CDD:212727
si:dkey-172h23.2	NP_957093.1	ANK repeat	163..197	CDD:293786	7/33 (21%)
		ANK	<165..218	CDD:238125	14/48 (29%)
		Ank_4	166..219	CDD:290365	14/47 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910