Protein Alignment: Zcchc7 and ZCCHC2

• Sequence 1: NP_648926.3
• Gene: Zcchc7
• FlyBaseID: FBgn0036668
• Length: 1734
• Species: Drosophila melanogaster
• Sequence 2: NP_060212.4
• Gene: ZCCHC2
• HGNCID: 22916
• Length: 1178
• Species: Homo sapiens
• Alignment Length: 645
• Identity: 123/646 (19%)
• Similarity: 226/646 (35%)
• Gaps: 163/646 (25%)

  Fly     4 LEEMDSERLNELESILYASIHYSDGFEEHTAMDQPAKESTSDQDARSMPPPPQQKHPIPGQRFVS 68
            |.::||    .|:|:..|....|.|..|    |:..::...:|||......|:
Human   195 LPQVDS----VLKSLRAARGEGSRGGAE----DERGEDGDGEQDAEKDGSGPE------------ 239

  Fly    69 GTRVINNSMQKPRYWIDGAAAVGEGQVVQAEEQQATTNKTMPAVEESSSSQSMDVDMPQDKSLLL 133
                  ..:.:||        ||.|...:|:|:.... .||.::..:.|.... |.:.:....|.
Human   240 ------GGIVEPR--------VGGGLGSRAQEELLLL-FTMASLHPAFSFHQR-VTLREHLERLR 288

  Fly   134 SPEKGTSNQPKTASQPPKHQQIPQAKQQQNIHAKQLQNQQAKPQEQKNSQQKQQQSLKQQNQQSK 198
            :..:|.....:...:|.|... |:| |..:.|...:||.::...||....|........:.|:..
Human   289 AALRGGPEDAEVEVEPCKFAG-PRA-QNNSAHGDYMQNNESSLIEQAPIPQDGLTVAPHRAQREA 351

  Fly   199 QH------QNQQKKSAPVVQKPKPQPNAS-------TKVNHEAYE----------AERFDQRLLV 240
            .|      :..|:|.|....:...:.|.|       ||.:.|..|          :|.||:.:|.
Human   352 VHIEKIMLKGVQRKRADKYWEYTFKVNWSDLSVTTVTKTHQELQEFLLKLPKELSSETFDKTILR 416

  Fly   241 AIPPNCPPKKQNKPQQNKQQQQQNKQQQKKQQQSLQHNKQQQQSGPGPFGKANRKLEQIQRLADK 305
            |:                  .|.:.::::::...|:...:|.      |..:::...|.|::...
Human   417 AL------------------NQGSLKREERRHPDLEPILRQL------FSSSSQAFLQSQKVHSF 457

  Fly   306 KQKSKQAQLNKKQRKQQSPPVEFV--NLAETSE--SSDDDDVVHVPL------PPAPII-ELDTS 359
            .|......|:.....|.|.....:  :|.|.|.  ||.::||:...:      ..:||: .:.||
Human   458 FQSISSDSLHSINNLQSSLKTSKILEHLKEDSSEASSQEEDVLQHAIIHKKHTGKSPIVNNIGTS 522

  Fly   360 ----DG---------------EQTCTSSQLFHEENAMDATD----VKMGLSCITEPEGTSVVASS 401
                ||               :|:||:.|  |.|:.:.:.|    .|..||.|.:.:|..
Human   523 CSPLDGLTMQYSEQNGIVDWRKQSCTTIQ--HPEHCVTSADQHSAEKRSLSSINKKKGKP----- 580

  Fly   402 TTPPMHSPSCSVMSSDDFIVQKDTTRLLTECENANDEDLLVLTETAIREAIGEEPKDKEVVENAS 466
                         .::...::|...||     |:....:.:.|.   :.|.|...||    .|..
Human   581 -------------QTEKEKIKKTDNRL-----NSRINGIRLSTP---QHAHGGTVKD----VNLD 620

  Fly   467 EEQEHDHAADTSSEYEFVPPSRLEEIKKNYRVDDQQFRALDVYESESD------LTESGIYSKAK 525
            ....||...:||||....|.|...:.::::..::::.|..|....:|.      .|..|..::..
Human   621 IGSGHDTCGETSSESYSSPSSPRHDGRESFESEEEKDRDTDSNSEDSGNPSTTRFTGYGSVNQTV 685

  Fly   526 SKTTPTIIRNVDSSSGSSSVEEVVEPSVQKTKRLRKRSCSTNNHSQSD------PNNDDG 579
            :...|..|.::.:.:|:...:.:..|..|....:....|..:|.:|..      |...||
Human   686 TVKPPVQIASLGNENGNLLEDPLNSPKYQHISFMPTLHCVMHNGAQKSEVVVPAPKPADG 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zcchc7	NP_648926.3	PTZ00368	827..937	CDD:173561
ZCCHC2	NP_060212.4	PX_domain	363..461	CDD:295365	21/122 (17%)
		zf-CCHC	1133..1148	CDD:278525

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG5082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900