Protein Alignment UQCR-C2 and UQCRC2

DIOPT Version :10

• Sequence 1: NP_648905.1
• Gene: UQCR-C2 / 39846
• FlyBaseID: FBgn0250814
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_003357.2
• Gene: UQCRC2 / 7385
• HGNCID: 12586
• Length: 453
• Species: Homo sapiens
• Alignment Length: 420
• Identity: 141/420 - (33%)
• Similarity: 222/420 - (52%)
• Gaps: 26/420 - (6%)

  Fly    37 LENKLVVATADATLPVSRVSLVLGAGSRNESYDIQGASHLLRLAGGLSTQNSTAFAIARNIQQVG 101
            |.|.||:|:.:...||||:.|.:.||||.|.:...|.:|||||...|:|:.:::|.|.|.|:.||
Human    43 LPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLTTKGASSFKITRGIEAVG 107

  Fly   102 GTLTTWGDRELVGYTVTTTADNAETGLRYLQDL-LQPAFKPWELVDNA------KTVVNQLNAVS 159
            |.|:....||.:.|||.....:.:..:.:|.:: ..|.|:.||:.|..      |.|..|    :
Human   108 GKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQPQLKIDKAVAFQ----N 168

  Fly   160 TEERAIELVHKAAFRNGLGNSIYSPRFQLGKLSSESLLHYVAQTFAAGRAAVVGVGIDNNTLAGF 224
            .:...||.:|.||:||.|.|.:|.|.:::||::||.|.::|...|.:.|.|::|:|:.:..|...
Human   169 PQTHVIENLHAAAYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQV 233

  Fly   225 A-QTLQFPSG-GSKAASANWYGGDARK---DTSGHRAVVAVAGQGAAASNHKEALAFAILEQALG 284
            | |.|....| |...|.||:.||:.|:   |:..|.|.||    .:|.:...||.||::|:..||
Human   234 AEQFLNMRGGLGLSGAKANYRGGEIREQNGDSLVHAAFVA----ESAVAGSAEANAFSVLQHVLG 294

  Fly   285 AKAATKRG--TSAGLFGEAVNCAGGVGASVKAVNASYSDAGLFGFVVSADSK---DIGKTVEFLV 344
            |....|||  |::.|. :||..|......|.|.||||||:||||....:.:.   |:.|.....|
Human   295 AGPHVKRGSNTTSHLH-QAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQV 358

  Fly   345 RGLKSASVSDKDVARGKALLKARIISRYSSDGGLIKEIGRQAALTRNVLEADALLGAIDGISQSQ 409
            :.:...::|:.||...|..|||..:....|....::|:|.||.:..:.:....:|..||.::.:.
Human   359 KTIAQGNLSNTDVQAAKNKLKAGYLMSVESSECFLEEVGSQALVAGSYMPPSTVLQQIDSVANAD 423

  Fly   410 VQEAAKKVGSSKLAVGAIGHLANVPYASDL 439
            :..||||..|.:.::.|.|:|.:.|:..:|
Human   424 IINAAKKFVSGQKSMAASGNLGHTPFVDEL 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UQCR-C2	NP_648905.1	PqqL	23..428	CDD:440377	137/407 (34%)
UQCRC2	NP_003357.2	PqqL	37..437	CDD:440377	136/402 (34%)
		Peptidase_M16	48..194	CDD:425812	52/149 (35%)