Protein Alignment UQCR-C2 and UQCRC1

DIOPT Version :10

• Sequence 1: NP_648905.1
• Gene: UQCR-C2 / 39846
• FlyBaseID: FBgn0250814
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_003356.2
• Gene: UQCRC1 / 7384
• HGNCID: 12585
• Length: 480
• Species: Homo sapiens
• Alignment Length: 460
• Identity: 107/460 - (23%)
• Similarity: 191/460 - (41%)
• Gaps: 52/460 - (11%)

  Fly     9 SLLRAIAKRGYATCPRPVGDLSAVNVKVLENKLVVATADATLPVSRVSLVLGAGSRNESYDIQGA 73
            :|||..|.|..||..:.:..:....|.:|:|.|.||:..::.|...|.:.:..|||.|:....||
Human    25 ALLRTPALRSTATFAQALQFVPETQVSLLDNGLRVASEQSSQPTCTVGVWIDVGSRFETEKNNGA 89

  Fly    74 SHLLRLAGGLSTQNSTAFAIARNIQQVGGTLTTWGDRELVGYTVTTTADNAETGLRYLQDLLQPA 138
            .:.|.......|:|....|:.:.::.:|..|..:..||...|.:...:.:....:..|.|::|..
Human    90 GYFLEHLAFKGTKNRPGSALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNC 154

  Fly   139 FKPWELVDNAKTVV---NQLNAVSTEERAIELVHKAAFR-NGLGNSIYSPRFQLGKLSSESLLHY 199
            ......::..:.|:   .|.|..|..:.....:|..||: ..|..::..|...:.|||...|..|
Human   155 SLEDSQIEKERDVILREMQENDASMRDVVFNYLHATAFQGTPLAQAVEGPSENVRKLSRADLTEY 219

  Fly   200 VAQTFAAGRAAVVGV-GIDNNTLAGFAQTLQFPSGG---SKAASA-------NWYGGDARKDTSG 253
            ::..:.|.|..:... |:::..|...||.   ..||   :.|..|       .:.|.:.|
Human   220 LSTHYKAPRMVLAAAGGVEHQQLLDLAQK---HLGGIPWTYAEDAVPTLTPCRFTGSEIR----- 276

  Fly   254 HR--------AVVAVAGQGAAASNHKEALAFAILEQALGAKAATKRG---TSAGLFGEAVNCAGG 307
            ||        ..:||.|.|.|:.::   :|..:....:|....|..|   .|:.|...||  |..
Human   277 HRDDALPFAHVAIAVEGPGWASPDN---VALQVANAIIGHYDCTYGGGVHLSSPLASGAV--ANK 336

  Fly   308 VGASVKAVNASYSDAGLFGFVVSADSKDIGKTVEFLVRG---LKSASVSDKDVARGKALLKARII 369
            :..|.:..:..|::.||.|.....|...|...: |:::|   ....|.::.:|||||.:|:..::
Human   337 LCQSFQTFSICYAETGLLGAHFVCDRMKIDDMM-FVLQGQWMRLCTSATESEVARGKNILRNALV 400

  Fly   370 SRYSSDGGLIKEIGRQAALTRN----VLEADALLGAIDGISQSQVQE-AAKKVGSSKLAVGAIGH 429
            |.......:.::||| :.||..    :.|.::.:..:|.   |.|:| .:|.:.....||...|.
Human   401 SHLDGTTPVCEDIGR-SLLTYGRRIPLAEWESRIAEVDA---SVVREICSKYIYDQCPAVAGYGP 461

  Fly   430 LANVP 434
            :..:|
Human   462 IEQLP 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UQCR-C2	NP_648905.1	PqqL	23..428	CDD:440377	98/438 (22%)
UQCRC1	NP_003356.2	PqqL	35..466	CDD:440377	101/448 (23%)