Protein Alignment Rpn12 and RPN12

DIOPT Version :10

• Sequence 1: NP_648904.1
• Gene: Rpn12 / 39845
• FlyBaseID: FBgn0028693
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_116710.1
• Gene: RPN12 / 850613
• SGDID: S000001948
• Length: 274
• Species: Saccharomyces cerevisiae
• Alignment Length: 281
• Identity: 82/281 - (29%)
• Similarity: 137/281 - (48%)
• Gaps: 24/281 - (8%)

  Fly     1 MANVESLYKELTAEWSKRPPNTVKCGQLLDQLKVALVKMAFLPTD---GNDAQSSKKQLILARSV 62
            |.::..|.|.|:..:..  .:...|.:||..:|:.|:|...|..|   .||...:  .|::.:.:
Yeast     1 MPSLAELTKSLSIAFEN--GDYAACEKLLPPIKIELIKNNLLIPDLSIQNDIYLN--DLMITKRI 61

  Fly    63 LEVAVEHSVLSKDLLAFERYMAQLKCYYYDYAKIIGESESKYKLLGLNLLYLLSGNRVSDFHTEL 127
            |||....|:.:.:..:||.|..|||.||:.....:.||:.|.||:.|.||.|||.|..:.||:||
Yeast    62 LEVGALASIQTFNFDSFENYFNQLKPYYFSNNHKLSESDKKSKLISLYLLNLLSQNNTTKFHSEL 126

  Fly   128 ELLSVDV--IQHNQFIRPILALEQYIMEGRYNK---IFQAKSTVPVEVYSYFMDLLLETVRDEIG 187
            :.|...:  ::.:..:...:.|::::|||.|.|   :.|:.|. .:..:..|.|:|...:||||.
Yeast   127 QYLDKHIKNLEDDSLLSYPIKLDRWLMEGSYQKAWDLLQSGSQ-NISEFDSFTDILKSAIRDEIA 190

  Fly   188 ACIEKSYDKISAKDAAKRLNLRVPDEIKAFGAKRQWKLEASGDYSFTDRSVKPK-----ELLPSE 247
            ...|.|||.:...:....|......|.:.|..:|.|.:..|..| |.::| |.|     |::..|
Yeast   191 KNTELSYDFLPLSNIKALLFFNNEKETEKFALERNWPIVNSKVY-FNNQS-KEKADYEDEMMHEE 253

  Fly   248 E----LAEQVLSYARDLEMIV 264
            :    :.|:.:.||..:|.||
Yeast   254 DQKTNIIEKAMDYAISIENIV 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpn12	NP_648904.1	CSN8_PSD8_EIF3K	119..229	CDD:462954	29/114 (25%)
RPN12	NP_116710.1	SAC3_GANP	122..226	CDD:474128	28/104 (27%)