Protein Alignment st and PDR18

DIOPT Version :10

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_014468.3
• Gene: PDR18 / 855807
• SGDID: S000005353
• Length: 1333
• Species: Saccharomyces cerevisiae
• Alignment Length: 658
• Identity: 179/658 - (27%)
• Similarity: 298/658 - (45%)
• Gaps: 113/658 - (17%)

  Fly    64 EQGATLVWRDLCVYTNVGGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAG 128
            |.....:|:::. :|....||||  :::::.:|...||||.||:|.||:|||||::|||.|. .|
Yeast   724 ESTGVFIWKNVS-FTIPHSSGQR--KLLDSVSGYCVPGTLTALIGESGAGKTTLLNTLAQRN-VG 784

  Fly   129 TVVQGDILINGRRIGPFMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKE- 192
            |:. ||:|::|..:.....|.:|||.|.||.:..|||.|.|.|.|.:|..:.:...|:...:::
Yeast   785 TIT-GDMLVDGLPMDASFKRRTGYVQQQDLHVAELTVKESLQFSARMRRPQSIPDAEKMEYVEKI 848

  Fly   193 --LLERTGLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNP-VILFCDEPTTGLDSYSAQQL 254
              :||......|....||.|     |:..:||:|:..|||:..| ::||.||||:||||.||..:
Yeast   849 ISILEMQEFSEALVGEIGYG-----LNVEQRKKLSIGVELVGKPDLLLFLDEPTSGLDSQSAWAV 908

  Fly   255 VATLYELAQKGTTILCTIHQPSSQLFDNFNNVMLLA-DGRVAFTG----SPQHALSFFANHG-YY 313
            |..|..||..|.:|||||||||:.||:.|:.::||. .|:..:.|    :....:.:|..:| ..
Yeast   909 VKMLKRLALAGQSILCTIHQPSATLFEQFDRLLLLGKGGQTIYFGEIGKNSSSVIKYFEKNGARK 973

  Fly   314 CPEAYNPADFL---IGVLAT---DPGYEQASQRSAQHLCDQFAVSSAAKQRDMLVNLE---IHMA 369
            |.:..|||:::   ||..||   ...:....|:|.::      .:...|..||:.:|.   :|..
Yeast   974 CQQNENPAEYILEAIGAGATASVQQNWPDIWQKSHEY------ANINEKINDMIKDLSSTTLHKT 1032

  Fly   370 QSGNFPFDTEVESFRGVAWYKRFHVVWLRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEP 434
            .:....:.|        ::..:||.|..|:|||..|:     |.:|....|..:|...|.|.|.
Yeast  1033 ATRASKYAT--------SYSYQFHHVLKRSSLTFWRN-----LNYIMAKMMLLMISGLFIGFTF- 1083

  Fly   435 SQLGVQAV--QGALF-----IMISENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAANIL 492
            ..:||.|:  |.:||     |:||....:.:.....:..:.:.  :||::|.::........:.|
Yeast  1084 FHVGVNAIGLQNSLFACFMAIVISAPATNQIQERATVAKELYE--VRESKSNMFHWSLLLITHYL 1146

  Fly   493 ALLPGMIIEPLIFVIICYWLTGLRSTFYAFGVTAMCVVLVMNVATACGCFFSTAFNSVPLAMAYL 557
            ..||..::...||.:..|:..|:      |...:...|..:|.|    ..|...:..:.|.:.|:
Yeast  1147 NELPYHLLFSTIFFVSSYFPLGV------FTEASRSSVFYLNYA----ILFQLYYIGLALMILYM 1201

  Fly   558 VP--------LDYI--FMITSGIFIQVNSLPVAFW--------WTQFLS---WMLYANEAMTAAQ 601
            .|        :.:|  |:::....:|..||...||        :|.||.   .:|..::.:..::
Yeast  1202 SPNLQSANVIVGFILSFLLSFCGAVQPASLMPGFWTFMWKLSPYTYFLQNLVGLLMHDKPVRCSK 1266

  Fly   602 WSGVQNITCFQESADLPC---------FHTG----QDVLDKYSFNESNVYRNLLAMVGLYFGFHL 653
                :.::.|.......|         |.||    .|.....::.:..|....||.:...|.:
Yeast  1267 ----KELSLFNPPVGQTCGEFTKPFFEFGTGYIANPDATADCAYCQYKVGDEYLARINASFSY-- 1325

  Fly   654 LGYYCLWR 661
                 |||
Yeast  1326 -----LWR 1328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	3a01204	67..665	CDD:273361	178/655 (27%)
PDR18	NP_014468.3	3a01205	1..1333	CDD:273362	179/658 (27%)