Protein Alignment st and Abcg1

DIOPT Version :10

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_445954.2
• Gene: Abcg1 / 85264
• RGDID: 620294
• Length: 666
• Species: Rattus norvegicus
• Alignment Length: 667
• Identity: 193/667 - (28%)
• Similarity: 328/667 - (49%)
• Gaps: 80/667 - (11%)

  Fly    31 IEVPSLDSTPKLSKRNSSE----RSLPLRSYSKWSPTEQGATLVWRDLCVYTNVGGSGQR---MK 88
            :|...|:...|....|.:|    .|||.|:         ...:.::||. |:...|...|   .|
  Rat    44 LETDLLNGHLKKVDNNFTEAQRFSSLPRRA---------AVNIEFKDLS-YSVPEGPWWRKKGYK 98

  Fly    89 RIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLA-FRQPAGTVVQGDILING--RRIGPFMHRIS 150
            .::...:|....|.|:|:||.||:||:|||:.|| :|:   |.::|.:||||  |.:..| .::|
  Rat    99 TLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRE---TGMKGAVLINGMPRDLRCF-RKVS 159

  Fly   151 GYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAAQTRIGSGDDKKV 215
            .|:.|||:.|..|||.|.:...|||:|..:  .|.||.::||:|...|||..|.||.||
  Rat   160 CYIMQDDMLLPHLTVQEAMMVSAHLKLQEK--DEGRREMVKEILTALGLLPCANTRTGS------ 216

  Fly   216 LSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTILCTIHQPSSQLF 280
            ||||:|||||.|:||:|||.::|.||||:||||.|..|:|:.:..|||.|.:|:|||||||::||
  Rat   217 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIVCTIHQPSAKLF 281

  Fly   281 DNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLATDPGYEQASQRSA--Q 343
            :.|:.:.:|:.|:..:.|...:.:.:..:.|..||..:|||||::.|.:.:.|.:.:....|  :
  Rat   282 ELFDQLYVLSQGQCVYRGKVSNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVRE 346

  Fly   344 HLCDQFAVSSAAKQRDMLVNLEIHMAQSGNF-------PFDTEVESFRG-----VAWYKRFHVVW 396
            .:||.              :.:..:...|:.       |.:.:..|..|     .:...:|.:::
  Rat   347 GMCDS--------------DYKRELGGDGDVNPFLWHRPAEEDSASMEGCHSFSASCLTQFCILF 397

  Fly   397 LRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQAVQGALFIMISENTYHPMYSV 461
            .|..|:::||..:..||....|.:..:||..:.|....:: .|.:..|.||..:....:..:...
  Rat   398 KRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAK-KVLSNSGFLFFSMLFLMFAALMPT 461

  Fly   462 LNLFPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVIICYWLTGLRSTFYAFGVTA 526
            :..||....:|:||..:..||...||.|..:|.:|..|:.|:.:..|.||:|...|....|.:.|
  Rat   462 VLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFA 526

  Fly   527 MCVVLVMNVATACGCFFSTAFNSVPLAMAYLVPLDYI-FMITSGIFIQVNSLPVAFWWTQFLSWM 590
            ....:...||.:.|.....|..|:.:| .::.|:..| .::.||.|:..:::|....|..::|::
  Rat   527 ALGTMTSLVAQSLGLLIGAASTSLQVA-TFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYV 590

  Fly   591 LYANEAMTAAQWSGVQNITCFQESADLPC-------FHTGQDVLDKYSFNESNVYRNLLAMVGLY 648
            .|..|.:..:.:.        .:..||.|       |...:.:|.:.....:.:|.:.: ::|::
  Rat   591 RYGFEGVILSIYG--------LDREDLHCDIAETCHFQKSEAILRELDVENAKLYLDFI-VLGIF 646

  Fly   649 F-GFHLLGYYCLWRRAR 664
            | ...|:.|:.|..:.|
  Rat   647 FISLRLIAYFVLRYKIR 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	3a01204	67..665	CDD:273361	184/627 (29%)
Abcg1	NP_445954.2	3a01204	60..666	CDD:273361	189/651 (29%)