Protein Alignment st and abcg2

DIOPT Version :10

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_012819987.2
• Gene: abcg2 / 734088
• XenbaseID: XB-GENE-991895
• Length: 682
• Species: Xenopus tropicalis
• Alignment Length: 622
• Identity: 184/622 - (29%)
• Similarity: 303/622 - (48%)
• Gaps: 78/622 - (12%)

  Fly    90 IINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQ-PAGTVVQGDILINGRRIGPFMHRISGYV 153
            |:|:..|.::|| |.|::|.:||||::|:..||.|: |.|  :.|.:|::|.........:||||
 Frog    82 ILNDVNGIMRPG-LNAILGPTGSGKSSLLDVLAARKDPNG--LSGQVLVDGEPQPSNFKCLSGYV 143

  Fly   154 YQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAAQTRIGSGDDKKVLSG 218
            .|||:.:|:|::.|:|.|.|.|||.|.|.::|:...|.::::..||...|.:::|:...:.| ||
 Frog   144 VQDDVVMGTLSIRENLQFSAALRLPRSVKQKEKDERINQVIKELGLTKVADSKVGTQFIRGV-SG 207

  Fly   219 GERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTILCTIHQPSSQLFDNF 283
            |||||....:||:.:|.|||.||||||||:.:|..::..|..::::|.||:.:||||...:|..|
 Frog   208 GERKRTNIGMELITDPGILFLDEPTTGLDASTANAVLLLLKRMSRQGKTIIFSIHQPRYSIFRLF 272

  Fly   284 NNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLATDPG--------------- 333
            :::.|||.||:.|.|..:.||.:|...||.|....|||||.:.::..|..
 Frog   273 DSLTLLAGGRLLFHGPSRDALDYFTGLGYECESHNNPADFFLDIINGDSTAVALNKLEDVELENE 337

  Fly   334 ----YEQASQRSAQHLCDQFAVSS-----AAKQRDMLVNLEIHMAQSGNFPFDTEVESFRGVAWY 389
                .:..|:...::|.:||..:|     .|:...|.:..:|    ..||       ..|.:.:.
 Frog   338 QKEVNDNGSKTVVENLSEQFCTTSYYLETKAELEKMSLGKKI----KSNF-------FARQITYN 391

  Fly   390 KRF--HVVWL--RASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQAVQGALFIMI 450
            ..|  .:.|:  |:...|.|:|.....:.:..:.:|.|:||.|.|..|... |:|...|:|| .:
 Frog   392 TSFLHQLKWVCKRSFKNLWRNPQASIAQVMVTLVLALIVGAIFFGVKEDVS-GIQNRVGSLF-FV 454

  Fly   451 SENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAANILA-LLPGMIIEPLIFVIICYWLTG 514
            :.|......|.:.||.....:|:.|..||.|....|:.|.:.. |||...:..:||..:.|::.|
 Frog   455 TTNQCFSSVSAIELFIVEKKIFIHEYISGYYRLSAYFFAKLFTDLLPMRTLPSIIFTSVIYFMIG 519

  Fly   515 LRSTFYAFGVTAMCVVLVMNVATACGCFFSTAFNSVPLAMA-YLVPLDYIFMIT-SGIFIQVNSL 577
            .::|..||  ..|...|:|...||.....:.|.....:|:| .|:.:.::|||. ||:.:.:.|
 Frog   520 FKATAGAF--FTMMFTLMMIAYTAASMALAVAAGQDVVAVANLLMTICFVFMIIFSGLLVNLTS- 581

  Fly   578 PVAFWWTQFLSWMLY---ANEAMTAAQWSGVQNI--------------TCFQESADLPCFHTGQD 625
             |..|    :||:.|   ....:||.|.:...|:              .|...|....|  ||::
 Frog   582 -VMDW----ISWLKYFSIPRYGLTALQINEFTNLNFCNGLNTTIQGNPNCTGSSPFGTC--TGEE 639

  Fly   626 VL--DKYSFNESNVYRNLLAMVGLYFGFHLLGYYCLW 660
            .|  ....|:...:::|.||:..:...|..:.|..|:
 Frog   640 YLTVQGIDFSTWGLWQNHLALACMIAIFLTIAYLKLY 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	3a01204	67..665	CDD:273361	184/622 (30%)
abcg2	XP_012819987.2	3a01204	73..675	CDD:273361	183/619 (30%)