Protein Alignment st and wht-1

DIOPT Version :10

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001348731.1
• Gene: wht-1 / 175859
• WormBaseID: WBGene00015479
• Length: 671
• Species: Caenorhabditis elegans
• Alignment Length: 683
• Identity: 224/683 - (32%)
• Similarity: 341/683 - (49%)
• Gaps: 70/683 - (10%)

  Fly    29 STIEVPSLDSTPKLSK-RNSSERSLPLRSYSKWSP-TEQGATLVWRDLCVYTNVGG--------- 82
            ||:.:.||.|...|:: .|..:..|.....:...| ..:|..|.|..|    ||.|
 Worm     7 STLILDSLFSNMMLAEMMNDDQLELLKHQQTGIQPVVPEGCNLYWSSL----NVTGPETKPTNFV 67

  Fly    83 -------SGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQGDILINGR 140
                   ..:|:|.|::|.:|..:.|.|:|::||||:||||||:.|..|......|||.|||:||
 Worm    68 DRFRNNMPKRRVKEILHNVSGMAESGKLLAILGSSGAGKTTLMNVLTSRNLTNLDVQGSILIDGR 132

  Fly   141 RIGPF-MHRISGYVYQDDLFLGSLTVLEHLNFMAHLRL-DRRVSKEERRLIIKELLERTGLLSAA 203
            |...: :..:|.:|.|.|:|:|::|..|||.|||.||: |:..|..||:|.::::|.:.||...|
 Worm   133 RANKWKIREMSAFVQQHDMFVGTMTAREHLQFMARLRMGDQYYSDHERQLRVEQVLTQMGLKKCA 197

  Fly   204 QTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTI 268
            .|.||..:..|.||.||:|||:||.|:|..|.||||||||:|||::.|..:|..|..||..|.|:
 Worm   198 DTVIGIPNQLKGLSCGEKKRLSFASEILTCPKILFCDEPTSGLDAFMAGHVVQALRSLADNGMTV 262

  Fly   269 LCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLATDPG 333
            :.|||||||.::..||||.|:|.|||.:.|....|:..|...||.||..|||||.||..||....
 Worm   263 IITIHQPSSHVYSLFNNVCLMACGRVIYLGPGDQAVPLFEKCGYPCPAYYNPADHLIRTLAVIDS 327

  Fly   334 YEQASQRSAQHLCDQF----------AVSSAAKQR--------DMLVNLEIHMAQSGNFPFDTEV 380
            ....|.::...:...|          |:.:|.|.|        |.....:....|..|..|.|:
 Worm   328 DRATSMKTISKIRQGFLSTDLGQSVLAIGNANKLRAASFVTGSDTSEKTKTFFNQDYNASFWTQ- 391

  Fly   381 ESFRGVAWYKRFHVVWLRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGT-TEPSQLGVQAVQG 444
              |..:.|         |:.||::|||.:..:|.:|.:..|||.|..|..| ..|:.  :.::.|
 Worm   392 --FLALFW---------RSWLTVIRDPNLLSVRLLQILITAFITGIVFFQTPVTPAT--IISING 443

  Fly   445 ALFIMISENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVIIC 509
            .:|..|....:...:..:.:.....|:.:||..:|:|.|..|:.|..:|.||..||.|:::..|.
 Worm   444 IMFNHIRNMNFMLQFPNVPVITAELPIVLRENANGVYRTSAYFLAKNIAELPQYIILPILYNTIV 508

  Fly   510 YWLTGLRSTFYAFGVTAMCVVLVMNVATACGCFFSTAFNSVPLAMA----YLVPLDYIFMITSGI 570
            ||::||...|:.:...::..:|:.|||.:.....:|.|.:..:||.    ::||:    |...|.
 Worm   509 YWMSGLYPNFWNYCFASLVTILITNVAISISYAVATIFANTDVAMTILPIFVVPI----MAFGGF 569

  Fly   571 FIQVNSLPVAFWWTQFLSWMLYANEAMTAAQWSGVQNI-TCFQESADL----PCFHTGQDVLDKY 630
            ||..:::|..|.|...||:..|..||:...:|..::.| .||..|...    .|...|..||:..
 Worm   570 FITFDAIPSYFKWLSSLSYFKYGYEALAINEWDSIKVIPECFNSSMTAFALDSCPKNGHQVLESI 634

  Fly   631 SFNESNVYRNLLAMVGLYFGFHLLGYYCLWRRA 663
            .|:.|:...::..:.|::.|..::.|..|..|:
 Worm   635 DFSASHKIFDISILFGMFIGIRIIAYVALLIRS 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	3a01204	67..665	CDD:273361	214/643 (33%)
wht-1	NP_001348731.1	3a01204	76..667	CDD:273361	207/608 (34%)