Protein Alignment st and Abcg8

DIOPT Version :10

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_569098.2
• Gene: Abcg8 / 155192
• RGDID: 620300
• Length: 672
• Species: Rattus norvegicus
• Alignment Length: 628
• Identity: 175/628 - (27%)
• Similarity: 286/628 - (45%)
• Gaps: 76/628 - (12%)

  Fly    69 LVWRDLCVYTNVGGSGQRMKRIINNSTGAIQPGTLMALMGSSGSGKTTLMSTLAFRQPAGTVVQG 133
            |.||.       .||.......|.|.:..::.|.::|::||:|.|:.||:..:..|...|.:..|
  Rat    73 LPWRS-------RGSQDSWDLGIRNLSFKVRSGQMLAIIGSAGCGRATLLDVITGRDHGGKMKSG 130

  Fly   134 DILINGRRIGP-FMHRISGYVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERT 197
            .|.|||:...| .:.:...:|.|.|..|.:|||.|.|.|:|.:||.:..|:.:|...:::::...
  Rat   131 QIWINGQPSTPQLIQKCVAHVRQQDQLLPNLTVRETLTFIAQMRLPKTFSQAQRDKRVEDVIAEL 195

  Fly   198 GLLSAAQTRIGSGDDKKVLSGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELA 262
            .|...|.||:|:...:.| |||||:|::..|:||.||.||..||||:||||::|..||.||..||
  Rat   196 RLRQCANTRVGNTYVRGV-SGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVRTLSRLA 259

  Fly   263 QKGTTILCTIHQPSSQLFDNFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGV 327
            :....:|.::|||.|.:|..|:.|:|:..|...:.|..||.:.:|.:.||.||...|||||.:.:
  Rat   260 KGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGVAQHMVQYFTSIGYPCPRYSNPADFYVDL 324

  Fly   328 LATD---PGYEQASQRSAQHLC----------DQFAVSSAAKQRDMLVNLEIHMAQSGNFPFDTE 379
            .:.|   ...|.|:...|:.|.          |.|...:.||..|...     .|.|.....||.
  Rat   325 TSIDRRSKEQEVATMEKARLLAALFLEKVQGFDDFLWKAEAKSLDTGT-----YAVSQTLTQDTN 384

  Fly   380 VESFRGVA-----WYKRFHVVWLRASLTLLRD-PTIQWLRFIQKIAMAFIIGACFAGTTEPSQLG 438
            .    |.|     ..::|..:..|......|| ||: ::...:...|:.|||..:.|..: ..|.
  Rat   385 C----GTAAELPGMIQQFTTLIRRQISNDFRDLPTL-FIHGAEACLMSLIIGFLYYGHAD-KPLS 443

  Fly   439 VQAVQGALFIMISENTYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPL 503
            ...:...||::.:...::.:..|::.......|...|...|||:.|.|:.|.:|..||......:
  Rat   444 FMDMAALLFMIGALIPFNVILDVVSKCHSERSLLYYELEDGLYTAGPYFFAKVLGELPEHCAYVI 508

  Fly   504 IFVIICYWLTGLRSTFYAFGVTAMCVVLVMNVATACGCFFSTAFNSVPLAMAYLVPLDYI----- 563
            |:.:..||||.||.....|.:..|.:.||:   ..|        .::.||.:.::|..::
  Rat   509 IYGMPIYWLTNLRPGPELFLLHFMLLWLVV---FCC--------RTMALAASAMLPTFHMSSFCC 562

  Fly   564 ------FMITSGIFIQVNSLPVAFWWTQFLSWMLYANEAMTAAQWSG------VQNITCFQESAD 616
                  |.:|:|..|.:|:|.:...|...:|::.:....:...|::|      :.|:|     ..
  Rat   563 NALYNSFYLTAGFMINLNNLWIVPAWISKMSFLRWCFSGLMQIQFNGHIYTTQIGNLT-----FS 622

  Fly   617 LPCFHTGQDVLDKYSFNESNVYRNLLAMVGLYFGFHLLGYYCL 659
            :|    |..::.....|...:|...|.::|:..||..|.|..|
  Rat   623 VP----GDAMVTAMDLNSHPLYAIYLIVIGISCGFLSLYYLSL 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	3a01204	67..665	CDD:273361	175/628 (28%)
Abcg8	NP_569098.2	ABCG_White	60..295	CDD:213201	82/229 (36%)
		3a01204	88..662	CDD:273361	170/606 (28%)