Protein Alignment st and Abcg1

DIOPT Version :10

• Sequence 1: NP_524108.1
• Gene: st / 39836
• FlyBaseID: FBgn0003515
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_033723.1
• Gene: Abcg1 / 11307
• MGIID: 107704
• Length: 666
• Species: Mus musculus
• Alignment Length: 675
• Identity: 196/675 - (29%)
• Similarity: 330/675 - (48%)
• Gaps: 96/675 - (14%)

  Fly    31 IEVPSLDSTPKLSKRNSSE----RSLPLRSYSKWSPTEQGATLVWRDLCVYTNVGGSGQR--MKR 89
            :|...|:...|....|.:|    .|||.|:         ...:.::||......|...::  .|.
Mouse    44 VETDLLNGHLKKVDNNFTEAQRFSSLPRRA---------AVNIEFKDLSYSVPEGPWWKKKGYKT 99

  Fly    90 IINNSTGAIQPGTLMALMGSSGSGKTTLMSTLA-FRQPAGTVVQGDILING--RRIGPFMHRISG 151
            ::...:|....|.|:|:||.||:||:|||:.|| :|:   |.::|.:||||  |.:..| .::|.
Mouse   100 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRE---TGMKGAVLINGMPRDLRCF-RKVSC 160

  Fly   152 YVYQDDLFLGSLTVLEHLNFMAHLRLDRRVSKEERRLIIKELLERTGLLSAAQTRIGSGDDKKVL 216
            |:.|||:.|..|||.|.:...|||:|..:  .|.||.::||:|...|||..|.||.||      |
Mouse   161 YIMQDDMLLPHLTVQEAMMVSAHLKLQEK--DEGRREMVKEILTALGLLPCANTRTGS------L 217

  Fly   217 SGGERKRLAFAVELLNNPVILFCDEPTTGLDSYSAQQLVATLYELAQKGTTILCTIHQPSSQLFD 281
            |||:|||||.|:||:|||.::|.||||:||||.|..|:|:.:..|||.|.:|:|||||||::||:
Mouse   218 SGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIVCTIHQPSAKLFE 282

  Fly   282 NFNNVMLLADGRVAFTGSPQHALSFFANHGYYCPEAYNPADFLIGVLATDPGYEQASQRSA--QH 344
            .|:.:.:|:.|:..:.|...:.:.:..:.|..||..:|||||::.|.:.:.|.:.:....|  :.
Mouse   283 LFDQLYVLSQGQCVYRGKVSNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREG 347

  Fly   345 LCDQFAVSSAAKQRDMLVNLEIHMAQSGNFPFDTEVESFRGVAWYK------------------- 390
            :||      |..:||:           |.   ||:|..|   .|::
Mouse   348 MCD------ADYKRDL-----------GG---DTDVNPF---LWHRPAEEDSASMEGCHSFSASC 389

  Fly   391 --RFHVVWLRASLTLLRDPTIQWLRFIQKIAMAFIIGACFAGTTEPSQLGVQAVQGALFIMISEN 453
              :|.:::.|..|:::||..:..||....|.:..:||..:.|....:: .|.:..|.||..:...
Mouse   390 LTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAK-KVLSNSGFLFFSMLFL 453

  Fly   454 TYHPMYSVLNLFPQGFPLFMRETRSGLYSTGQYYAANILALLPGMIIEPLIFVIICYWLTGLRST 518
            .:..:...:..||....:|:||..:..||...||.|..:|.:|..|:.|:.:..|.||:|...|.
Mouse   454 MFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSD 518

  Fly   519 FYAFGVTAMCVVLVMNVATACGCFFSTAFNSVPLAMAYLVPLDYI-FMITSGIFIQVNSLPVAFW 582
            ...|.:.|....:...||.:.|.....|..|:.:| .::.|:..| .::.||.|:..:::|....
Mouse   519 AVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVA-TFVGPVTAIPVLLFSGFFVSFDTIPAYLQ 582

  Fly   583 WTQFLSWMLYANEAMTAAQWSGVQNITCFQESADLPC-------FHTGQDVLDKYSFNESNVYRN 640
            |..::|::.|..|.:..:.:.        .:..||.|       |...:.:|.:.....:.:|.:
Mouse   583 WMSYISYVRYGFEGVILSIYG--------LDREDLHCDIAETCHFQKSEAILRELDVENAKLYLD 639

  Fly   641 LLAMVGLYF-GFHLLGYYCLWRRAR 664
            .: ::|::| ...|:.|:.|..:.|
Mouse   640 FI-VLGIFFISLRLIAYFVLRYKIR 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
st	NP_524108.1	3a01204	67..665	CDD:273361	187/635 (29%)
Abcg1	NP_033723.1	3a01204	60..666	CDD:273361	192/659 (29%)