Protein Alignment Agpat4 and AGPAT5

DIOPT Version :10

• Sequence 1: NP_648887.1
• Gene: Agpat4 / 39819
• FlyBaseID: FBgn0036622
• Length: 380
• Species: Drosophila melanogaster
• Sequence 2: NP_060831.2
• Gene: AGPAT5 / 55326
• HGNCID: 20886
• Length: 364
• Species: Homo sapiens
• Alignment Length: 350
• Identity: 86/350 - (24%)
• Similarity: 160/350 - (45%)
• Gaps: 64/350 - (18%)

  Fly     6 GLGRLLIAVTFFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYYLHYSFYCI----LVCVAEWYAG 66
            |:.|||.|  |....|:            :..|.:|            ||:    ::...|.|.|
Human    33 GVWRLLSA--FLPARFY------------QALDDRL------------YCVYQSMVLFFFENYTG 71

  Fly    67 SKLRVYID-PQDEQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLG 130
            .::.:|.| |::      ||:.:.|.||...:||:.|.::..:...||..:...|:.|:::|:.|
Human    72 VQILLYGDLPKN------KENIIYLANHQSTVDWIVADILAIRQNALGHVRYVLKEGLKWLPLYG 130

  Fly   131 WVWWMAEFIFLDRNFEKDKVVIKTQLKEVFSYPDPVWLLLNAEGTRFTPAKHEL---SVKFAEER 192
            ..:.....|::.|:.:.::..::.:|:.......|::|::..||||:.|.:.::   |..||.:|
Human   131 CYFAQHGGIYVKRSAKFNEKEMRNKLQSYVDAGTPMYLVIFPEGTRYNPEQTKVLSASQAFAAQR 195

  Fly   193 GLPLLKHHLIPRTKGFTTSLPTMRGICPAIYDINLAFKKNAE-----PKPTMLSQLNGEPVEPYM 252
            ||.:|||.|.||.|....:...|:....||||:.:.::...:     ..|||...|..|..:.::
Human   196 GLAVLKHVLTPRIKATHVAFDCMKNYLDAIYDVTVVYEGKDDGGQRRESPTMTEFLCKECPKIHI 260

  Fly   253 YIRRVPLDVVPDDEKEAAAWMQDFFAEKDKIIDSFHETGSFFKNSGVKEVPEKIYKPRLS---TL 314
            :|.|:....||::::....|:.:.|..|||::..|:|:....:.   |..|.|....:||   ||
Human   261 HIDRIDKKDVPEEQEHMRRWLHERFEIKDKMLIEFYESPDPERR---KRFPGKSVNSKLSIKKTL 322

  Fly   315 LNFLGWATFAVLCILHYLVTSLVAG 339
            .:.|             :::.|.||
Human   323 PSML-------------ILSGLTAG 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_648887.1	PLN02380	12..366	CDD:178006	81/343 (24%)
AGPAT5	NP_060831.2	LPLAT_LCLAT1-like	63..263	CDD:153252	53/205 (26%)
		HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q9D517	93..98		1/4 (25%)
		Acyltransf_C	258..312	CDD:465006	14/56 (25%)