Protein Alignment Agpat4 and LCLAT1

DIOPT Version :10

• Sequence 1: NP_648887.1
• Gene: Agpat4 / 39819
• FlyBaseID: FBgn0036622
• Length: 380
• Species: Drosophila melanogaster
• Sequence 2: NP_872357.2
• Gene: LCLAT1 / 253558
• HGNCID: 26756
• Length: 414
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 101/369 - (27%)
• Similarity: 167/369 - (45%)
• Gaps: 41/369 - (11%)

  Fly    14 VTFFTCGFFVNIGQL---LLILLVRPFDKKLSRSLAYY------LHYSFYCILVCVAEWYAGSKL 69
            :|.|...||.:|..|   |.::.|.|         ::|      |..::..:.|.:.|...|.|:
Human    49 LTLFWGSFFGSIFMLSPFLPLMFVNP---------SWYRWINNRLVATWLTLPVALLETMFGVKV 104

  Fly    70 RVYIDPQDEQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLGWVWW 134
            .:..|     .|...|..:::|||...:||:..|....:...|...|...|..|:.||..||...
Human   105 IITGD-----AFVPGERSVIIMNHRTRMDWMFLWNCLMRYSYLRLEKICLKASLKGVPGFGWAMQ 164

  Fly   135 MAEFIFLDRNFEKDKVVIKTQLKEVFSYPDPVWLLLNAEGTRFTPAKHELSVKFAEERGLPLLKH 199
            .|.:||:.|.::.||...:..:.......:|:.||:..|||..|......|..|||:.||...::
Human   165 AAAYIFIHRKWKDDKSHFEDMIDYFCDIHEPLQLLIFPEGTDLTENSKSRSNAFAEKNGLQKYEY 229

  Fly   200 HLIPRTKGFTTSLPTMR--GICPAIYDINLAFKKNAEPKPTMLSQLNGE-PVEPYMYIRRVPLDV 261
            .|.|||.|||..:..:|  ....|::||.:|:..|.......|  |.|: |.|.:.::.|.|:|.
Human   230 VLHPRTTGFTFVVDRLREGKNLDAVHDITVAYPHNIPQSEKHL--LQGDFPREIHFHVHRYPIDT 292

  Fly   262 VPDDEKEAAAWMQDFFAEKDKIIDSFHETGSFFKNSGVKEVP--EKIYKPRLSTLLNFLGWATFA 324
            :|..:::...|....:.||::.:.||::....|..:|...:|  :...:..:..||:.|.|..|:
Human   293 LPTSKEDLQLWCHKRWEEKEERLRSFYQGEKNFYFTGQSVIPPCKSELRVLVVKLLSILYWTLFS 357

  Fly   325 -VLCILHYLVTSLVAGNWFGFITVL------SILGGFYSLMEYA 361
             .:|:|.||. |||  .|:..||::      .|.||. .::|.|
Human   358 PAMCLLIYLY-SLV--KWYFIITIVIFVLQERIFGGL-EIIELA 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_648887.1	PLN02380	12..366	CDD:178006	101/369 (27%)
LCLAT1	NP_872357.2	LPLAT_LCLAT1-like	93..286	CDD:153252	58/199 (29%)
		HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q9D517	123..128		1/4 (25%)
		Acyltransf_C	271..345	CDD:465006	17/75 (23%)