DRSC/TRiP Functional Genomics Resources

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Protein Alignment Agpat4 and Lpgat1

DIOPT Version :10

Sequence 1:NP_648887.1 Gene:Agpat4 / 39819 FlyBaseID:FBgn0036622 Length:380 Species:Drosophila melanogaster
Sequence 2:NP_001128301.1 Gene:Lpgat1 / 226856 MGIID:2446186 Length:409 Species:Mus musculus


Alignment Length:405 Identity:91/405 - (22%)
Similarity:151/405 - (37%) Gaps:125/405 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 LIAVTFFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYY---LHYSFYCILVCVAEWYAGSKLRVY 72
            |:|:..:.|  :|.|.|.|.:|..:.|         :|   |.|.:...:|....||||..:   
Mouse    69 LVAIPSYIC--YVIILQPLRVLDSKRF---------WYIEGLMYKWLLGMVASWGWYAGYTV--- 119

  Fly    73 IDPQDEQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLGWVWWMAE 137
            ::..::.|...|:..::|:||....|..|..|.....|                ||:..:.|:.:
Mouse   120 MEWGEDIKAIAKDEAVMLVNHQATGDVCTLMMCLQDKG----------------PVVAQMMWLMD 168

  Fly   138 FIFLDRNF-------------------EKDKVVIKTQLKEVFSYPDPVWLLLNAEGTRFTPAKHE 183
            .||...||                   ::..:|:|..|:..:...|..|::|..|| .|...:.|
Mouse   169 HIFKYTNFGIVSLIHGDFFIRQGRAYRDQQLLVLKKHLEHNYRSRDRKWIVLFPEG-GFLRKRRE 232

  Fly   184 LSVKFAEERGLPLLKHHLIPRTKGFTTSLPTM--------------RGI-CPA-----IYDINLA 228
            .|..||::..||.|.|..:||.......|..:              ||: |.:     |.|..:|
Mouse   233 TSQAFAKKNNLPFLTHVTLPRFGATNIILKALVARQENGSPAGGDARGLECKSRGLQWIIDTTIA 297

  Fly   229 FKKNAEP-----------KPTMLSQLNGEPVEPYMYIRRVPLDVVPDDEKEAAAWMQDFFAEKDK 282
            :.| |||           |||:          .:::.|..|:..||.:.::..:|:...|.||:.
Mouse   298 YPK-AEPIDIQTWILGYRKPTV----------THVHYRIFPIGDVPLETEDLTSWLYQRFIEKED 351

  Fly   283 IIDSFHETGSFFKNSGVKEVPEKIYKPRLSTLLNFLGWATFAVLCILHYLVTSLVAGNWFGFITV 347
            ::..|::||:|....|.||.     ..|..||.|.                       |...|..
Mouse   352 LLSHFYKTGAFPPPQGQKEA-----VCREMTLSNM-----------------------WIFLIQS 388

  Fly   348 LSILGGF--YSLMEY 360
            .:.|.|:  |.:::|
Mouse   389 FAFLSGYLWYHIIQY 403

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Agpat4NP_648887.1 PLN02380 12..366 CDD:178006 90/404 (22%)
Lpgat1NP_001128301.1 LPLAT_LCLAT1-like 108..324 CDD:153252 54/246 (22%)
Acyltransf_C 313..383 CDD:465006 22/107 (21%)

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