Protein Alignment Tcs3 and KAE1

DIOPT Version :10

• Sequence 1: NP_648880.1
• Gene: Tcs3 / 39811
• FlyBaseID: FBgn0283681
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_012964.2
• Gene: KAE1 / 853910
• SGDID: S000001746
• Length: 386
• Species: Saccharomyces cerevisiae
• Alignment Length: 372
• Identity: 225/372 - (60%)
• Similarity: 278/372 - (74%)
• Gaps: 32/372 - (8%)

  Fly     4 ALGIEGSANKIGIGIIR----------------DGKVLANVRRTYITPPGEGFLPKETAKHHREA 52
            |||:||||||:|:||::                :.::|:|:|.||:|||||||||::||:|||..
Yeast    18 ALGLEGSANKLGVGIVKHPLLPKHANSDLSYDCEAEMLSNIRDTYVTPPGEGFLPRDTARHHRNW 82

  Fly    53 ILGLVESSLKEAQLKSS--DLDVICYTKGPGMAPPLLVGAIVARTLSLLWNIPLLGVNHCIGHIE 115
            .:.|::.:|.||.:||.  |:||||:||||||..||....|.|||.||||::||:||||||||||
Yeast    83 CIRLIKQALAEADIKSPTLDIDVICFTKGPGMGAPLHSVVIAARTCSLLWDVPLVGVNHCIGHIE 147

  Fly   116 MGRLITGAQNPTVLYVSGGNTQVIAYSNKRYRIFGETIDIAVGNCLDRFARIIKLSNDPSPGYNI 180
            |||.||.||||.|||||||||||||||.|||||||||:|||:|||||||||.:|:.|:|||||||
Yeast   148 MGREITKAQNPVVLYVSGGNTQVIAYSEKRYRIFGETLDIAIGNCLDRFARTLKIPNEPSPGYNI 212

  Fly   181 EQLAKSS---NRYIKLPYVVKGMDVSFSGILSYIEDLAE---PGKRQNK---RKKPQEEEVNNYS 236
            |||||.:   ...::|||.|||||:|.||||:.|:.||:   .|.::||   .|...|::|   :
Yeast   213 EQLAKKAPHKENLVELPYTVKGMDLSMSGILASIDLLAKDLFKGNKKNKILFDKTTGEQKV---T 274

  Fly   237 QADLCYSLQETIFAMLVEITERAMAHCGSNEVLIVGGVGCNERLQEMMRIMCEER-GGKLFATDE 300
            ..||||||||.:||||||||||||||..||:||||||||||.||||||..||::| .|::.|||.
Yeast   275 VEDLCYSLQENLFAMLVEITERAMAHVNSNQVLIVGGVGCNVRLQEMMAQMCKDRANGQVHATDN 339

  Fly   301 RYCIDNGLMIAHAGAEMFR-SGTRMPFEESYVTQRFRTDEVLVSWRD 346
            |:|||||:|||.||...:| .|....|.|:.|||:||||||..:|||
Yeast   340 RFCIDNGVMIAQAGLLEYRMGGIVKDFSETVVTQKFRTDEVYAAWRD 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tcs3	NP_648880.1	ASKHA_NBD_OSGEP_like_euk	3..321	CDD:466982	210/345 (61%)
KAE1	NP_012964.2	ASKHA_NBD_OSGEP_like_euk	17..360	CDD:466982	210/344 (61%)