Protein Alignment Tcs3 and OSGEPL1

DIOPT Version :10

• Sequence 1: NP_648880.1
• Gene: Tcs3 / 39811
• FlyBaseID: FBgn0283681
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: XP_024308807.1
• Gene: OSGEPL1 / 64172
• HGNCID: 23075
• Length: 425
• Species: Homo sapiens
• Alignment Length: 345
• Identity: 107/345 - (31%)
• Similarity: 164/345 - (47%)
• Gaps: 38/345 - (11%)

  Fly     5 LGIEGSANKIGIGIIRD-GKVLANV--RRTYITPPGEGFLPKETAKHHREAILGLVESSLKEAQL 66
            ||||.|.:.....::.: |.||...  .:|.:.....|.:|....:.|||.|..:|:.:|..:.:
Human    51 LGIETSCDDTAAAVVDETGNVLGEAIHSQTEVHLKTGGIVPPAAQQLHRENIQRIVQEALSASGV 115

  Fly    67 KSSDLDVICYTKGPGMAPPLLVGAIVARTLSLLWNI--PLLGVNHCIGHIEMGRLITGAQNP-TV 128
            ..|||..|..|..||:|..|.||  ::.:|.|:..:  |.:.::|...|....||....:.| .|
Human   116 SPSDLSAIATTIKPGLALSLGVG--LSFSLQLVGQLKKPFIPIHHMEAHALTIRLTNKVEFPFLV 178

  Fly   129 LYVSGGNTQV-IAYSNKRYRIFGETIDIAVGNCLDRFARIIKLSNDP-----SPGYNIEQLAKSS 187
            |.:|||:..: :......:.:.|:::|||.|:.||:.||.:.|...|     |.|..||.|||..
Human   179 LLISGGHCLLALVQGVSDFLLLGKSLDIAPGDMLDKVARRLSLIKHPECSTMSGGKAIEHLAKQG 243

  Fly   188 NRY---IKLP-YVVKGMDVSFSGILSYIEDLAEPGKRQNKRKKPQEEEVNN----YSQADLCYSL 244
            ||:   ||.| :..|..|.||:| |.::.|       :...||.:||.:..    .|.||:..::
Human   244 NRFHFDIKPPLHHAKNCDFSFTG-LQHVTD-------KIIMKKEKEEGIEKGQILSSAADIAATV 300

  Fly   245 QETIFAMLVEITERAMAHC-------GSNEVLIV-GGVGCNERLQEMMRIMCEERGGKLFATDER 301
            |.|:...||:.|.||:..|       .:|.||:. |||..|..::..:.|:.......|.....|
Human   301 QHTMACHLVKRTHRAILFCKQRDLLPQNNAVLVASGGVASNFYIRRALEILTNATQCTLLCPPPR 365

  Fly   302 YCIDNGLMIAHAGAEMFRSG 321
            .|.|||:|||..|.|..|:|
Human   366 LCTDNGIMIAWNGIERLRAG 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tcs3	NP_648880.1	ASKHA_NBD_OSGEP_like_euk	3..321	CDD:466982	106/343 (31%)
OSGEPL1	XP_024308807.1	ASKHA_NBD_OSGEPL1_QRI7_euk	50..384	CDD:466984	105/342 (31%)