Protein Alignment CG4950 and lingo1b

DIOPT Version :8

• Sequence 1: NP_001261934.1
• Gene: CG4950 / 39783
• FlyBaseID: FBgn0036587
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001004576.1
• Gene: lingo1b / 447837
• ZFINID: ZDB-GENE-040912-136
• Length: 622
• Species: Danio rerio
• Alignment Length: 577
• Identity: 128/578 (22%)
• Similarity: 217/578 (38%)
• Gaps: 105/578 (18%)

  Fly    13 ILILAISS-CDGSGGDIPLRCDEYDSMGYMDVNEAFCTVTGFTVT-HSQNVVIKNIPPGNMV--K 73
            ||||.:.: ..||....|.||:              |:....:|. |.:.::  .:|.|..:  :
Zfish    28 ILILMLGTVLSGSATGCPSRCE--------------CSAQERSVVCHRRKLI--TLPEGIPIDTR 76

  Fly    74 FMKFYESTLLYMPFHLFETFPYLKTLDVSNTNILELTRNAFSAASNLTYLNLAYNNLTSIQTSVF 138
            .:...::.|..:....|..:|.|:.|.::...|..:...|||....|..|.|..|||..||..||
Zfish    77 LLDLSKNRLKAINPEEFLNYPQLEDLQLNENIISVIEPGAFSNLLGLRTLGLRNNNLKLIQLGVF 141

  Fly   139 IGANVLMRLDLSYNEISSLSVNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLT 203
            .|.:.|.|||:|.|:|..|....|..|:.:.::.:..|.|..:.:..|.....||:::.|...||
Zfish   142 TGLSNLTRLDISENKIVILLDYMFQELYNLKELEVGDNDLVFISHRAFHGLSSLEQLTMERCNLT 206

  Fly   204 SIQPEVFRNMRRIKEVNLSNNRLIFIHPDTFADAASLENLVLSYNELKNFQLTEKNIVHQLHLDN 268
            |:..|.|.::..:..:.|.:..:..|...:|.....|:.|     |:.|:.|.|......||
Zfish   207 SVPTEAFSHLHNLLTLKLRHLNVNVIRDFSFRRLYRLKIL-----EIANWPLLESLTAKSLH--- 263

  Fly   269 NYLTNLTINATRFVRASHNQISELFLHQSLHIETLDLSANKLSSISNITNITHMLYL---DVSDN 330
                                        .|:|.||.::...|:::..:. |.|::||   ::|.|
Zfish   264 ----------------------------GLNITTLSITNCNLTAVPYVA-IQHLVYLRFFNLSFN 299

  Fly   331 PIGPLNISTFSQLKRLRGLNLRGTGIRELKFGMFSKQKYLEELDLSFNNLTILNLDMFVPYLTNL 395
            ||..:..:....|.||:..:|.|..:..::...|....||..|::|.|:|:.|....| ..:.||
Zfish   300 PIEVVEGNKMHNLLRLQAFHLVGGRLVSIEPYSFKGLNYLRVLNVSSNSLSTLEESAF-HSVGNL 363

  Fly   396 KKFLIDGNGLTELQGNRTFSEAFPQLQKLGVSRNRFNCSYLHHLLIPPSLPESVVLNIEPDTNLD 460
            :...:..|.|.            ...:.|.|.|.|:.                  ||........
Zfish   364 ETLALHDNPLA------------CDCRLLWVFRRRWR------------------LNFNRQQPSC 398

  Fly   461 ETPHIRDVSCISQSQEVVNAS-FTAEESKL-----------ESQIQMLSKQLDIVGSHSKNLELH 513
            |||............:|:..: ||.::||:           |........|.|  |..:..:...
Zfish   399 ETPEFLQGKEFKDFPDVLPPNYFTCQKSKIRDHKAIHRFVDEGTTVQFPCQAD--GDPTPMIMWQ 461

  Fly   514 LAFMQIFAYVMGGLVLVGVVSLITLRYLKNQRSGRYDRSSIVFRSNATMEANLTLGS 570
            ....|.......|.:.|.:...:.:||.:.|.:|.|...::....|.|..|:|.:.|
Zfish   462 SPKKQFITTKSIGRLSVSLDGTLEVRYAQIQDNGTYTCFAVNAGGNDTRLAHLHVHS 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4950	NP_001261934.1	leucine-rich repeat	96..119	CDD:275380	6/23 (26%)
		LRR_8	118..178	CDD:290566	22/60 (37%)
		leucine-rich repeat	120..143	CDD:275380	11/23 (48%)
		leucine-rich repeat	144..167	CDD:275380	10/23 (43%)
		leucine-rich repeat	168..191	CDD:275380	3/23 (13%)
		LRR_8	192..250	CDD:290566	14/58 (24%)
		leucine-rich repeat	192..215	CDD:275380	8/23 (35%)
		LRR_RI	<207..432	CDD:238064	48/228 (21%)
		leucine-rich repeat	216..239	CDD:275380	3/23 (13%)
		leucine-rich repeat	240..299	CDD:275380	9/59 (15%)
		LRR_8	299..356	CDD:290566	17/60 (28%)
		leucine-rich repeat	300..321	CDD:275380	5/21 (24%)
		leucine-rich repeat	322..345	CDD:275380	7/26 (27%)
		LRR_8	344..405	CDD:290566	16/61 (26%)
		leucine-rich repeat	346..365	CDD:275380	4/19 (21%)
		leucine-rich repeat	370..394	CDD:275380	7/24 (29%)
		leucine-rich repeat	395..420	CDD:275380	3/25 (12%)
lingo1b	NP_001004576.1	LRRNT	43..77	CDD:214470	8/50 (16%)
		LRR 1	74..95		2/21 (10%)
		leucine-rich repeat	75..98	CDD:275380	3/23 (13%)
		LRR_8	76..133	CDD:290566	14/57 (25%)
		LRR_RI	78..>315	CDD:238064	67/274 (24%)
		LRR 2	98..119		6/21 (29%)
		leucine-rich repeat	99..146	CDD:275380	17/47 (36%)
		LRR 3	122..143		10/21 (48%)
		LRR_8	130..181	CDD:290566	19/51 (37%)
		LRR 4	146..167		9/21 (43%)
		leucine-rich repeat	147..170	CDD:275380	10/23 (43%)
		LRR_8	170..226	CDD:290566	12/56 (21%)
		LRR 5	170..191		3/21 (14%)
		leucine-rich repeat	171..194	CDD:275380	3/23 (13%)
		LRR 6	194..215		8/21 (38%)
		leucine-rich repeat	195..218	CDD:275380	8/23 (35%)
		LRR 7	218..239		3/21 (14%)
		leucine-rich repeat	219..242	CDD:275380	3/23 (13%)
		leucine-rich repeat	243..290	CDD:275380	15/84 (18%)
		LRR_8	266..325	CDD:290566	17/60 (28%)
		LRR 8	266..287		5/22 (23%)
		LRR 9	290..311		6/21 (29%)
		leucine-rich repeat	291..338	CDD:275380	11/47 (23%)
		LRR_8	314..373	CDD:290566	16/60 (27%)
		LRR 10	314..335		5/21 (24%)
		LRR 11	338..359		8/22 (36%)
		leucine-rich repeat	339..362	CDD:275380	7/24 (29%)
		TPKR_C2	371..424	CDD:301599	14/83 (17%)
		IG_like	438..516	CDD:214653	16/80 (20%)
		Ig	441..516	CDD:299845	15/77 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000238
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000