DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsynbetaL and Kdm6b

DIOPT Version :9

Sequence 1:	NP_648836.2	Gene:	ATPsynbetaL / 39761	FlyBaseID:	FBgn0036568	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	XP_030101676.1	Gene:	Kdm6b / 216850	MGIID:	2448492	Length:	1642	Species:	Mus musculus

Alignment Length:	180	Identity:	38/180 - (21%)
Similarity:	58/180 - (32%)	Gaps:	57/180 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VSWAKMATACARIGLKMGPGTG--------GYRGNYLGNPVVFPRYLHASLSLWD--------DK 51
            |.|.:....|..|...:||.|.        .|..|.:.|.......:|.|   |:        |.
Mouse  1468 VHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEVKNVKSIVPMIHVS---WNVARTVKISDP 1529

  Fly    52 DKKKSGDECEPEPQEVCKTDAELV----KK-------KDEAEDECEE----------KKSDGGGK 95
            |..|....|..:..:.|:...|.:    ||       |||....|.|          ..|:.|.:
Mouse  1530 DLFKMIKFCLLQSMKHCQVQRESLVRAGKKIAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSR 1594

  Fly    96 -----------KLESKGRKGVIHAVIGPVIDVYFEEEVPEVLNALQVQDA 134
                       :..|.|.:||:      |::.|..||:.:..:|..:..|
Mouse  1595 NTYLVHCEGCARRRSAGLQGVV------VLEQYRTEELAQAYDAFTLAPA 1638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynbetaL	NP_648836.2	PRK09280	103..568	CDD:236447	8/32 (25%)
		ATP-synt_ab_N	106..173	CDD:280947	6/29 (21%)
		F1-ATPase_beta	175..454	CDD:238553
		ATP-synt_ab_C	462..571	CDD:278722
Kdm6b	XP_030101676.1	TPR repeat	106..136	CDD:276809
		JmjC	1342..1406	CDD:214721
		JmjC	1376..1484	CDD:396791	4/15 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0055
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900