DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsynbetaL and Kdm5d

DIOPT Version :9

Sequence 1:	NP_648836.2	Gene:	ATPsynbetaL / 39761	FlyBaseID:	FBgn0036568	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_035549.1	Gene:	Kdm5d / 20592	MGIID:	99780	Length:	1548	Species:	Mus musculus

Alignment Length:	176	Identity:	43/176 - (24%)
Similarity:	60/176 - (34%)	Gaps:	66/176 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   486 GMDELSEEDKLTVARARKMQRFLSQPFQVAEIFTGHPGKLVPVEKCVEGFKRL-------LNGEY 543
            |.|.|.||::|.:...|         .:.:|       |:||.|...:|.|.|       |.|..
Mouse  1336 GKDILKEEEELVLNEER---------IKSSE-------KIVPKESSCKGDKELLPSLLSQLTGPV 1384

  Fly   544 DDIPEIA------FYMVGDAEEVLAKAT----QLAASMSGDAPPAK-----AEAKKDEKKDTKPE 593
            .::||..      ..|.||..||.....    ||.  .:|..|..:     .|.:|.|    .|.
Mouse  1385 LELPEATRAPLEELMMEGDLLEVTLDENYSIWQLL--QAGQNPNLERIHTLLELEKPE----NPG 1443

  Fly   594 EGKKEEPP--------------KGED--------KKEEAKDDKPKE 617
            ...:|:.|              ||||        |:.::...||||
Mouse  1444 NWSEEQTPERRRQRRQKVVLSRKGEDFTQKELESKRVKSSRIKPKE 1489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynbetaL	NP_648836.2	PRK09280	103..568	CDD:236447	25/98 (26%)
		ATP-synt_ab_N	106..173	CDD:280947
		F1-ATPase_beta	175..454	CDD:238553
		ATP-synt_ab_C	462..571	CDD:278722	26/101 (26%)
Kdm5d	NP_035549.1	JmjN	13..54	CDD:128818
		BRIGHT	80..170	CDD:128777
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..229
		PHD1_KDM5C_5D	325..370	CDD:277077
		JmjC	500..616	CDD:202224
		zf-C5HC2	706..758	CDD:280996
		PLU-1	771..1094	CDD:285609
		PHD_SF	1182..1242	CDD:304600
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1438..1468		6/33 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0055
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900