Protein Alignment Hip14 and Patsas

DIOPT Version :10

• Sequence 1: NP_001261910.1
• Gene: Hip14 / 39747
• FlyBaseID: FBgn0259824
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_319681.3
• Gene: Patsas / 1279899
• VectorBaseID: AGAMI1_010831
• Length: 539
• Species: Anopheles gambiae
• Alignment Length: 623
• Identity: 170/623 - (27%)
• Similarity: 275/623 - (44%)
• Gaps: 134/623 - (21%)

  Fly    16 PGTGQQPDNERQSALIAQQPPTAPVEPDYSG--FDIVKATQYGAIARVRELVES-GWD-VNQPDS 76
            |...:.|..|:.|.|:|:...:..:......  ||::|:   |.::.|..|||. |.: ::..|.
Mosquito    12 PEEAKTPTQEKDSNLLARTDSSEVLIQSSMDDIFDVIKS---GELSEVENLVEKVGQEALSARDK 73

  Fly    77 ETVTLLHWAAINNRRDIIRYFLEKGATVD-AVGGELNATPLHWATRQGHLGAVVLLMAAGADPRI 140
            ...|..||||::...:::||.:|:.|.|| ...|.....|:|||.|:||...|.:|:.||.....
Mosquito    74 HGYTPAHWAALDGNVEMMRYLVERNAPVDLPCLGTQGPRPIHWACRKGHAAVVQVLLQAGVAVNA 138

  Fly   141 RDAEGCSCIHIAAQFAHTALVAYFIAKGVDPDLQDRGGMTALMWAAWKVCALDPVRLLLTLGANP 205
            .|.:|.:.:..|..:..||..||.:..|....|.|..|.|||.|||:|..| |.:|||:..|.:.
Mosquito   139 ADFKGLTPLMTACMYGRTATAAYLLGMGAQNHLTDINGDTALHWAAYKGHA-DLIRLLMYSGVDL 202

  Fly   206 AMVDYTHGNTALHWAILARNATAISTLVLKSKASLDVPNLRGETPLSMLESQTGAIWIGAKVMDR 270
            ...| ..|:|.||.|.|:.|...:..|..|....|:..:..|:||:.:.:|
Mosquito   203 QKTD-NFGSTPLHLACLSGNLQCVKILCEKRNLELEPRDKNGKTPVMLAQS-------------- 252

  Fly   271 VKEAALTSQQRRSLLSKLRHD---KRLRW-------WSMVACPFTAFYLAGIVFTVNTLYIIKFF 325
                     .|.|.:.||.|:   |:.||       |.|:      |..||.......|:::...
Mosquito   253 ---------HRNSEVVKLLHNEMKKKSRWMPPISEIWGML------FGGAGASKGPLILFLVSVL 302

  Fly   326 LLGCLYSIFHTIGKALFDEHLMALLPLSVYLATKAWFYVTWLMYIDDAVSFTATVCFLISSLLLW 390
            |.|             :..:::..:|            :||      .:...:..||:..:.::|
Mosquito   303 LWG-------------YPMYMIRCIP------------ITW------NILRRSHYCFIYWNAVMW 336

  Fly   391 VCFLKSWKGDPGIIRPTREQRFKTIIEL------SERGGIGFEPASFCSGCLVRRPIRSKHCSVC 449
            :.::.:.:.|||.|....:..::.|.::      .:|..|   .:..|..|...||:|:|||.:|
Mosquito   337 ISWIIANRRDPGYIPLNSDTYYRAIKQIPYFDKWKKRNII---LSRLCHSCRCLRPLRAKHCRIC 398

  Fly   450 DRCVARFDHHCPWVGNCIGLKNHSYFMGFLWMLLIMCAWMLY---------GGSKYYVNQCNVRF 505
            :|||:.||||||::.||:||:|..:|:.|:..:.|.|::.:|         |.|..||
Mosquito   399 NRCVSYFDHHCPFIYNCVGLRNRMWFLLFVLSIAINCSFTIYFACYCVMIEGFSLLYV------- 456

  Fly   506 DDFLGAMRAIGNCDAWVGWVMG-NALLHMSWVILLTICQTYQVICLGMTTNERMNRGRYRHFQAK 569
               ||.:.|...|.  :||::. .::||               .|:.:||||..|..||.:.:.|
Mosquito   457 ---LGLLEAFVFCG--LGWILTCTSILH---------------ACMNLTTNEMFNYKRYPYLRDK 501

  Fly   570 GG--HSPFTRGPIQNLVDFLECSCFGLVQPKRVDWMNY 605
            .|  .:||:|||:.||.:|..|      .|.|.|..:|
Mosquito   502 RGRYQNPFSRGPVLNLFEFFVC------LPDRQDDQDY 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hip14	NP_001261910.1	ANKYR	<52..246	CDD:440430	65/196 (33%)
		ANK repeat	77..108	CDD:293786	11/31 (35%)
		ANK repeat	110..142	CDD:293786	11/31 (35%)
		ANK repeat	144..175	CDD:293786	8/30 (27%)
		ANK repeat	177..209	CDD:293786	14/31 (45%)
		ANK repeat	212..244	CDD:293786	10/31 (32%)
		DHHC	426..559	CDD:396215	45/142 (32%)
Patsas	XP_319681.3	None