Protein Alignment CG17028 and IMPA2

DIOPT Version :10

• Sequence 1: NP_648822.1
• Gene: CG17028 / 39741
• FlyBaseID: FBgn0036552
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_055029.1
• Gene: IMPA2 / 3613
• HGNCID: 6051
• Length: 288
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 101/272 - (37%)
• Similarity: 149/272 - (54%)
• Gaps: 19/272 - (6%)

  Fly    11 EVYYQVSLELVRKCGPLFLEGFQKPKTDYEVKSAFYDLVTVYDKQIEATLTDGLLKTFPESKIIG 75
            |..:|.:::|..:.|.:..:...:.|. ...|::..||||..|..:|..:...|.:.||..:.|.
Human    17 EECFQAAVQLALRAGQIIRKALTEEKR-VSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIA 80

  Fly    76 EEAMAN-AKTPPELTDAPTWIIDPIDGTNNYVRKIPHCCISVGLAINKELVLGIVYNPSANELYS 139
            |||.|: ||.  .||.:|||||||||||.|:|.:.|...:|:|.|:.:||..|::|:.:...||:
Human    81 EEAAASGAKC--VLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYT 143

  Fly   140 AWQGHGAYLNGQPIEVSNAKKINQALVCYEISLIVVSKGRD--------KNVKRLYKLASSATGT 196
            ..:|.||:.|||.:.||....:::|||..||     ...||        .|::||  |.:.|.|.
Human   144 GRRGRGAFCNGQRLRVSGETDLSKALVLTEI-----GPKRDPATLKLFLSNMERL--LHAKAHGV 201

  Fly   197 RSFGCAALTLCYIAAGRCDAYHVENLKPWDLAGGAVILREAGGRVYHTSGARFDVMKPDCVCTSS 261
            |..|.:.|.||::|:|..|||:...|..||||...||:|||||.|..|||...|:|....|..|:
Human   202 RVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAAST 266

  Fly   262 EELAKSVIQLIE 273
            .|:|..:.|.::
Human   267 REMAMLIAQALQ 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17028	NP_648822.1	IMPase	13..260	CDD:238817	96/255 (38%)
IMPA2	NP_055029.1	IMPase	19..265	CDD:238817	96/255 (38%)