Protein Alignment CG17028 and IMPA1

DIOPT Version :10

• Sequence 1: NP_648822.1
• Gene: CG17028 / 39741
• FlyBaseID: FBgn0036552
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_001138350.1
• Gene: IMPA1 / 3612
• HGNCID: 6050
• Length: 336
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 97/291 - (33%)
• Similarity: 162/291 - (55%)
• Gaps: 29/291 - (9%)

  Fly     3 YRIGEEKLEV-YYQ-----------VSLELVRKCGPLFLEGFQKPKTDYEVKSAFYDLVTVYDKQ 55
            |..|:.|:.| |:|           .::.|.|:.|.:..|.. |.:.:..:||:..||||..|::
Human    45 YGFGKMKIFVKYFQKMADPWQECMDYAVTLARQAGEVVCEAI-KNEMNVMLKSSPVDLVTATDQK 108

  Fly    56 IEATLTDGLLKTFPESKIIGEEAMANAKTPPELTDAPTWIIDPIDGTNNYVRKIPHCCISVGLAI 120
            :|..|...:.:.:|....||||::| |.....|||.|||||||||||.|:|.:.|...:|:|.|:
Human   109 VEKMLISSIKEKYPSHSFIGEESVA-AGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAV 172

  Fly   121 NKELVLGIVYNPSANELYSAWQGHGAYLNGQPIEVSNAKKINQALVCYEIS--------LIVVSK 177
            ||::..|:||:....::|:|.:|.||:.|||.::||..:.|.::|:..|:.        .:|:|
Human   173 NKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLS- 236

  Fly   178 GRDKNVKRLYKLASSATGTRSFGCAALTLCYIAAGRCDAYHVENLKPWDLAGGAVILREAGGRVY 242
                |:::|:.:  ...|.||.|.||:.:|.:|.|..|||:...:..||:||..:|:.||||.:.
Human   237 ----NMEKLFCI--PVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLM 295

  Fly   243 HTSGARFDVMKPDCVCTSSEELAKSVIQLIE 273
            ..:|..||:|....:..::..||:.:.:.|:
Human   296 DVTGGPFDLMSRRVIAANNRILAERIAKEIQ 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17028	NP_648822.1	IMPase	13..260	CDD:238817	90/265 (34%)
IMPA1	NP_001138350.1	IMPase	67..313	CDD:238817	88/254 (35%)