Protein Alignment CG7579 and GALNT4

DIOPT Version :10

• Sequence 1: NP_648799.1
• Gene: CG7579 / 39714
• FlyBaseID: FBgn0036528
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_003765.2
• Gene: GALNT4 / 8693
• HGNCID: 4126
• Length: 578
• Species: Homo sapiens
• Alignment Length: 545
• Identity: 173/545 - (31%)
• Similarity: 247/545 - (45%)
• Gaps: 116/545 - (21%)

  Fly     1 MTETDLVDAQLQNEKYQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPH 65
            :.|.:|...:...|:|..|.:||:||.|.|.:||.|..:|....::.....|.|::||...|...
Human    85 LNEDELKQQEELIERYAINIYLSDRISLHRHIEDKRMYECKSQKFNYRTLPTTSVIIAFYNEAWS 149

  Fly    66 TLLRGIYSVITQTSP-YLLKEIVLVHDGHPDLDLIRHIHHKLPIVIQLEMESS------------ 117
            ||||.|:||: :||| .|||||:||.|          :..::.:..|||...|
Human   150 TLLRTIHSVL-ETSPAVLLKEIILVDD----------LSDRVYLKTQLETYISNLDRVRLIRTNK 203

  Fly   118 -KGIIHARLTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFA-YR 180
             :|::.|||.||..||||:|.||:.|.|...|||.||||.|..:...|..|::|.|...:|. |.
Human   204 REGLVRARLIGATFATGDVLTFLDCHCECNSGWLEPLLERIGRDETAVVCPVIDTIDWNTFEFYM 268

  Fly   181 KLVEPEQLAFDWQLDHIFLPLDQHSWNSLPK-----------PYPSSQLEGRVFAIDRKWFWHLG 234
            ::.||....|||:|        ...|:|:||           |..|..:.|.:||:.:|:|.:||
Human   269 QIGEPMIGGFDWRL--------TFQWHSVPKQERDRRISRIDPIRSPTMAGGLFAVSKKYFQYLG 325

  Fly   235 GWDEGLRDYGGDALELSLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNPSLQVQKNFKRV 299
            .:|.|:..:||:.||||.:||||||.:...|||.||.::.:      .||...|:.  .:|..|.
Human   326 TYDTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHVFPK------RAPYARPNF--LQNTARA 382

  Fly   300 VDVWLDEYKLHFYRYNPKLRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAPQ------------- 351
            .:||:||||.|||..||..|......:.:.:.||.||.||||:||...|.|.
Human   383 AEVWMDEYKEHFYNRNPPARKEAYGDISERKLLRERLRCKSFDWYLKNVFPNLHVPEDRPGWHGA 447

  Fly   352 IRNHFLHAGLTNY------PIGKIMPFVAPHFCLSIKGGFPVIRKCHSTN----FEDWTLTSRCQ 406
            ||:..:.:...:|      |.|.         .||:.|       ||...    ||   .||..:
Human   448 IRSRGISSECLDYNSPDNNPTGA---------NLSLFG-------CHGQGGNQFFE---YTSNKE 493

  Fly   407 LKHGN---MCLDV-DYKNNVRATKCTKKLSKNP----WHYNYQHSSFVSNGNKCLQI-------- 455
            ::..:   :|.:| :.||.|....|.|.....|    ||:....:.|..:...||..
Human   494 IRFNSVTELCAEVPEQKNYVGMQNCPKDGFPVPANIIWHFKEDGTIFHPHSGLCLSAYRTPEGRP 558

  Fly   456 DVNKVGLILSACDSDVTEQRWMFTK 480
            ||.     :..||:....|.|.|.|
Human   559 DVQ-----MRTCDALDKNQIWSFEK 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	pp-GalNAc-T	54..349	CDD:133004	120/320 (38%)
		beta-trefoil_Ricin_Pgant8-like	364..479	CDD:467339	31/140 (22%)
GALNT4	NP_003765.2	Catalytic subdomain A	134..243		48/119 (40%)
		pp-GalNAc-T	138..432	CDD:133004	120/320 (38%)
		Catalytic subdomain B	303..365		28/61 (46%)
		beta-trefoil_Ricin_GALNT4	442..577	CDD:467347	33/158 (21%)