DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and Galnt15

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	XP_006519762.1	Gene:	Galnt15 / 78754	MGIID:	1926004	Length:	652	Species:	Mus musculus

Alignment Length:	514	Identity:	154/514 - (29%)
Similarity:	233/514 - (45%)	Gaps:	78/514 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 NAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHTLLRGIYSVITQTSPYLL 83
            |..||.|:||:|.|.:.|.|.||: .:.:....|.|:::....|...||||.::|::......||
Mouse   160 NKPLSARLPLRRVLPEVRHPLCLQ-QHPTSGLPTASVILCFHDEAWPTLLRTVHSILDTAPRALL 223

  Fly    84 KEIVLVHD-GHPDL--DLIRHIHHKLPIVIQLEMESSKGIIHARLTGAGVATGDILVFLNGHMEV 145
            :||:||.| ...:|  ..:.....:|..|..|......|.|.||:.||..||||:|||::.|.|.
Mouse   224 QEIILVDDLSQQELLKSALSEYVARLEAVKLLRSNRRLGTIGARMLGATRATGDVLVFMDAHCEC 288

  Fly   146 TRGWLPPLLEPILLNNQTVTEPIVDAISRESFAY--RKLVEPEQLAFDWQLDHIFLPLDQHSWNS 208
            ..|||.|||..|..:...|..|::|.|..::..|  .||   .:...||:||..:.||.:....:
Mouse   289 HPGWLEPLLSRIADDRSRVVSPVIDVIDWKTLQYSASKL---HRGTLDWKLDFRWKPLGEQEQKA 350

  Fly   209 LPKPYP---SSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELSLKVWQCGGLILAVPCSRVG 270
            ||.|..   |..:...|.|:||.:|.:.|.:|..|.....:.||:|.|.|.|||.:..:||||||
Mouse   351 LPSPISPVRSPVVPREVVAVDRHYFQNTGAYDPLLSLGDSENLEMSFKAWLCGGSVEILPCSRVG 415

  Fly   271 IIYKRDELEAQMAPNRNPSLQVQKNFKRVVDVWLDEYKLHFYRYNPKLRNLTAESLDKP-----R 330
            .||:..  :|...|:...:|   ||...:.:.||..:|..|||:.|:.  .|...:.||     .
Mouse   416 HIYRSQ--DASSRPDPEVAL---KNKIIIAETWLSSFKETFYRHIPEA--FTLSKVAKPDCTERL 473

  Fly   331 DLRRRLNCKSFEWYRSQVAPQI-----RNHF---LHAGLTNYPIGKIMPFVAPHFCLSIKG---- 383
            .|:|||.|::|.|:.:.|.|::     |..|   ||    |...|         .|...:.
Mouse   474 KLQRRLGCRTFHWFLANVYPELYPSDHRPRFSGKLH----NTGFG---------LCADCQADGDI 525

  Fly   384 -GFPV-IRKCHSTNFEDWTL---------------TSRCQLKHG---NMCLDVDYKNNVRATKCT 428
             |.|: :..|.:...:..||               |.|.::..|   .:|.|| ....|....||
Mouse   526 LGCPMTLAPCSNNRQQQGTLLAMLTATPSAQNLEHTGRKEILFGGPQRLCFDV-RGGRVILQNCT 589

  Fly   429 KK-LSKNPWHYNYQHSSFVSN--GNKCLQIDV---NKVGLILSACDSDVTEQRWMFTKV 481
            :: .:.:..|:::|....:.:  ..||::..|   || .|.|..||.. |.|.|.|.::
Mouse   590 EEGPAIHQQHWDFQEDGMIIHVLSGKCMEAGVQPSNK-DLYLRQCDGK-TSQLWRFDQI 646

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	99/296 (33%)
		pp-GalNAc-T	54..349	CDD:133004	103/307 (34%)
		RICIN	367..478	CDD:238092	30/140 (21%)
		Ricin_B_lectin	373..476	CDD:279046	28/132 (21%)
Galnt15	XP_006519762.1	pp-GalNAc-T	194..492	CDD:133004	103/307 (34%)
Galnt15	XP_006519762.1	Ricin_B_lectin	504..641	CDD:366226	33/152 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842544
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740