DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and poc1bl

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001038243.2	Gene:	poc1bl / 503760	ZFINID:	ZDB-GENE-050306-41	Length:	582	Species:	Danio rerio

Alignment Length:	529	Identity:	162/529 - (30%)
Similarity:	251/529 - (47%)	Gaps:	88/529 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTETDLVDAQLQNEKYQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPH 65
            :|..:..:.:...|:...|.::|::|.|.|.::|.|..:|....|:..:..|.|:|||...|...
Zfish    90 LTSEEKKEEEASVERCAINIFISDKISLHRHIQDNRMHECKAKKYNIRRLPTTSVVIAFYNEAWS 154

  Fly    66 TLLRGIYSVITQTSPYLLKEIVLVHD----GHPDLDLIRHIHHKLPIVIQLEMESSKGIIHARLT 126
            ||||.|:||:..|...|||:|:||.|    |:....|.::|.: |..|..:..:..:|::.|||.
Zfish   155 TLLRTIHSVLETTPAVLLKDIILVDDFSDRGYLKSQLAQYISN-LERVRLIRTKKREGLVRARLI 218

  Fly   127 GAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFA-YRKLVEPEQLAF 190
            ||..|||.:|.||:.|.|...||:.||||.|..|..|:..|::|.|...:|. |.:..||....|
Zfish   219 GATYATGSVLTFLDCHCECVPGWIEPLLERIAENETTIICPVIDTIDWNTFEFYMQTEEPMVGGF 283

  Fly   191 DWQLDHIFLPLDQHSWNSLPK-----------PYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYG 244
            ||:|        ...|:::|:           |..|..:.|.:||:.:.:|.:||.:|.|:..:|
Zfish   284 DWRL--------TFQWHAVPEIDRKIRKSRIDPIRSPTMAGGLFAVSKAYFEYLGTYDMGMEVWG 340

  Fly   245 GDALELSLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAP-NRNPSLQVQKNFKRVVDVWLDEYK 308
            |:.||||.:||||||.:...|||.||.::.:      .|| .|:..||   |..|..:||:|.||
Zfish   341 GENLELSFRVWQCGGSLEIHPCSHVGHVFPK------KAPYARSNFLQ---NTVRAAEVWMDTYK 396

  Fly   309 LHFYRYNPKLRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAP-------------QIRNHFLHAG 360
            .|||..||..|..:...:.:...||.||.|||||||...|.|             .:|:..:|:.
Zfish   397 QHFYNRNPPARKESYGDISERIVLRNRLQCKSFEWYLQNVYPGLHVPEDRPGWHGAVRSAGIHSE 461

  Fly   361 LTNY------PIGKIMPFVAPHFCLSIKGGFPVIRKCHSTN----FEDWTLTSRCQLKHGN---M 412
            ..:|      |.|       .|  ||:.|       ||...    ||   .||:.:::..:   :
Zfish   462 CLDYNAPDHNPTG-------AH--LSLFG-------CHGQGGNQYFE---YTSQREIRFNSVTEL 507

  Fly   413 CLDV-DYKNNVRATKCTKK-LSKNP---WHYNYQHSSFVSNGNKCL---QIDVNKVGLILSACDS 469
            |.:| |...::....|.:. :.|.|   |.:....|.|..:.|.|:   :.:..:..:.:.:|.:
Zfish   508 CAEVQDGMTHIGMKHCPQDGVPKPPSIIWQFREDGSIFHPHSNMCITSYRTEEGRADIQMRSCST 572

  Fly   470 DVTEQRWMF 478
            ....|||.|
Zfish   573 GDKHQRWSF 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	109/300 (36%)
		pp-GalNAc-T	54..349	CDD:133004	117/311 (38%)
		RICIN	367..478	CDD:238092	26/125 (21%)
		Ricin_B_lectin	373..476	CDD:279046	23/117 (20%)
poc1bl	NP_001038243.2	WcaA	139..434	CDD:223539	118/312 (38%)
		pp-GalNAc-T	143..437	CDD:133004	117/311 (38%)
		RICIN	451..581	CDD:238092	30/148 (20%)
		Ricin_B_lectin	451..579	CDD:279046	28/146 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910