DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and Galntl5

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001020319.1	Gene:	Galntl5 / 499968	RGDID:	1565271	Length:	443	Species:	Rattus norvegicus

Alignment Length:	372	Identity:	130/372 - (34%)
Similarity:	200/372 - (53%)	Gaps:	28/372 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KYQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHTLLRGIYSVITQTS 79
            :|..|...|.|:.::|.:.|.|:..|.:.:|.. ...|.|::|....|..:||||.:.||:..:.
  Rat    85 RYGLNVITSRRLGIERQVPDSRNKICQQKHYPF-NLPTASVIICFYNEEFNTLLRTVSSVMNLSP 148

  Fly    80 PYLLKEIVLVHDGHPDLDLIRHIHHKLPI----VIQLEMESSKGIIHARLTGAGVATGDILVFLN 140
            .:||:||:||.|.....||...:.:.|.|    :..:..:..:|:|.:|:.||..|:|||||||:
  Rat   149 KHLLEEIILVDDMSEFDDLKAKLDYHLEIFRGKIKLVRNKKREGLIRSRMIGASRASGDILVFLD 213

  Fly   141 GHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAY--RKLVEPEQLAFDWQL----DHIF- 198
            .|.||.|.||.|||..|..:::.|..|::|.|...:..|  ..:|..   ||||.|    |.:|
  Rat   214 SHCEVNRVWLEPLLHAIAKDHKMVVCPVIDVIDELTLDYVGSPIVRG---AFDWNLNFRWDDVFS 275

  Fly   199 LPLDQHSWNSLPKPYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELSLKVWQCGGLILA 263
            ..||.....|.|...|:  :.|.:|||:|.:|..||.:|:.:..:||:.:||||::|.|||.:..
  Rat   276 YELDGPEGPSTPIRSPA--MSGGIFAINRHYFNELGQYDKDMDLWGGENVELSLRIWMCGGQLFI 338

  Fly   264 VPCSRVGIIYKRDELEAQMAPNRNPSLQVQKNFKRVVDVWLDEYKLHFYRYNPKLRNLTAESLDK 328
            :||||||  :....|......|::   .:.||..|||.|||||||.:|:...|.|.:::..::..
  Rat   339 LPCSRVG--HNNKALSKNRLVNQS---ALSKNLLRVVHVWLDEYKENFFLQRPSLTHVSCGNISD 398

  Fly   329 PRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTNYPI----GKIMP 371
            ..:||:||.||||:||...:.|::..  |:.|....|.    ||.:|
  Rat   399 RVELRKRLGCKSFQWYLDNIFPELEP--LNRGKGTKPFLLAKGKNVP 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	106/294 (36%)
		pp-GalNAc-T	54..349	CDD:133004	113/305 (37%)
		RICIN	367..478	CDD:238092	3/5 (60%)
		Ricin_B_lectin	373..476	CDD:279046
Galntl5	NP_001020319.1	pp-GalNAc-T	123..419	CDD:133004	113/305 (37%)
Galntl5	NP_001020319.1	Glyco_tranf_2_3	123..355	CDD:290369	87/238 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346040
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740