DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7579 and Pgant35A

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_652069.2	Gene:	Pgant35A / 48775	FlyBaseID:	FBgn0001970	Length:	632	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	149/503 - (29%)
Similarity:	234/503 - (46%)	Gaps:	74/503 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 YQYNAWLSERIPLKRTLEDYRDPQC-LKINYSSEKTVTVSIVIAIQQEHPHTLLRGIYSVITQTS 79
            :.:||.:|..|.|.|.:.|.|...| .:....:|.....|||:....||..||:|.|.:|:.:|.
  Fly   112 HAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTP 176

  Fly    80 PYLLKEIVLVHDGHPDL-DLIRHIHHKLPIVIQ------LEMESSKGIIHARLTGAGVATGDILV 137
            .|||:||:|| |.|.|| :|..|:|..|...::      ::.|..:|:|.:|:.||..|.||:||
  Fly   177 SYLLREIILV-DDHSDLPELEFHLHGDLRARLKYDNLRYIKNEQREGLIRSRVIGAREAVGDVLV 240

  Fly   138 FLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQL---AFDWQLDHIFL 199
            ||:.|:||.:.||.|||..|...|.|:..|::|.|:.::|.|    .|..|   .|:|.|
  Fly   241 FLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINADTFEY----TPSPLVRGGFNWGL----- 296

  Fly   200 PLDQHSWNSLPK-----------PYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELSLK 253
               ...|.:||:           |:.|..:.|.:||::||:|.|||.:|..:..:||:.:|:|.:
  Fly   297 ---HFRWENLPEGTLKVPEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFR 358

  Fly   254 VWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNP--SLQVQKNFKRVVDVWLDEYKLHFYRYNP 316
            .|||||.|..|||||||.|:::      ..|..:|  :..:.||..|:..||:|:||.::.::..
  Fly   359 AWQCGGAIKIVPCSRVGHIFRK------RRPYTSPDGANTMLKNSLRLAHVWMDQYKDYYLKHEK 417

  Fly   317 KLRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHF----------------LHAGLTNYP 365
            ..:......:.....||.||.|:.|.||...|.|::  |.                .|:...||.
  Fly   418 VPKTYDYGDISDRLKLRERLQCRDFAWYLKNVYPEL--HVPGEESKKSAAAPIFQPWHSRKRNYV 480

  Fly   366 IGKIMPFVAPHFCLSI----------KGGFPVIRKCHSTNFEDWTLTSRCQLKHGN-MCLDVDYK 419
            ....:.......|.::          ||....::.|..|..:.|..|.:.::.... :||:....
  Fly   481 DTFQLRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCRRTPNQLWYETEKAEIVLDKLLCLEASGD 545

  Fly   420 NNVRATKCTKKLSKNPWHYNYQHSSFVSNGNK--CLQIDVNKVGLILS 465
            ..|...||.:.|....|.:....:|.|.|..|  ||:......|.::|
  Fly   546 AQVTVNKCHEMLGDQQWRHTRNANSPVYNMAKGTCLRAAAPTTGALIS 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	105/306 (34%)
		pp-GalNAc-T	54..349	CDD:133004	111/317 (35%)
		RICIN	367..478	CDD:238092	22/112 (20%)
		Ricin_B_lectin	373..476	CDD:279046	22/106 (21%)
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	111/317 (35%)
		RICIN	489..610	CDD:214672	22/105 (21%)
		RICIN	490..609	CDD:238092	22/104 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457038
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840