Protein Alignment mrn and gtf-2H4

DIOPT Version :10

• Sequence 1: NP_648780.1
• Gene: mrn / 39688
• FlyBaseID: FBgn0261109
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001263824.1
• Gene: gtf-2H4 / 178431
• WormBaseID: WBGene00013529
• Length: 485
• Species: Caenorhabditis elegans
• Alignment Length: 522
• Identity: 156/522 - (29%)
• Similarity: 255/522 - (48%)
• Gaps: 73/522 - (13%)

  Fly     1 MADTKSGSGRHSAAGGSGNAVLSPLGQGPANLECKDFQEYLRTRQTPESLEKLYNYPPICLAVFR 65
            |:..:..:..|.....|.|:.|              |.::|.| ..|::.::|...|.....::|
 Worm     1 MSSDQPAAAPHLTGTSSKNSCL--------------FLDFLIT-IPPKTRQRLLQKPSCAFFIYR 50

  Fly    66 ELPEIARQFIIRILFVDQ-PVPQAVVTSWGAQRCAKEQAEATSCLTALNVWRVTAIPGGLSAWEL 129
            .||.||:|..|::::... |....|..:       ||..:....|..|.:.......|.|:   :
 Worm    51 MLPPIAQQTTIQLIWKGSFPTASDVEET-------KEIEDQVKLLKDLGLVHRQTTDGKLN---I 105

  Fly   130 SPTFKKS-VRQVLLGGGKPWPMT------NTLDKDSKPRDIAFLDTYAMSRWRCVLHYMVGTGNR 187
            ...:|:| :...:||..:...:.      |...||        ::..|:.||.|:|.|:......
 Worm   106 DTDYKRSYMYAAMLGAAQISSLVLEPNEGNRRGKD--------VEKKAVERWDCILRYLALPSEE 162

  Fly   188 NGTDAEAISPDAVRILLHANLMKRDERDGITITRQGFQFLLLDTRAQVWHFMLQYLDTCEERGIS 252
            |   .:|:|.....:...||.....:.. |.||..|||||||....|:|.::::||.....:|..
 Worm   163 N---TQAVSETTRNLFKKANFTSGGDTQ-IEITTFGFQFLLLSPVKQMWTYVIEYLKLEMSQGQD 223

  Fly   253 LPECLSMLFQL----------SFSTLGRDYS-----SEGMNSQMLTFLQHLREFGLVFQRKRKEG 302
            :.|.:..|.|:          .|......|.     :|..|.    .|.||||.|::|.||||:|
 Worm   224 IVEVIEPLIQIVLLANRVQVAGFKAERECYQIDANWTEPQNE----LLNHLRELGVIFIRKRKDG 284

  Fly   303 RFYPTRLALNVTSKEAAATASVAMDEEATQDCGYIVVETNYRVYAYTDSPLQVAVLGLFTELLYR 367
            .|:.|:|..::.:.|.....|.   |:.:.  |.::||||:||||||.|.||:|::.||||:.||
 Worm   285 VFFLTQLLTHLATNETIDDVSA---EKVSN--GKVIVETNFRVYAYTSSLLQLAIIALFTEMTYR 344

  Fly   368 FPNLVVGVLTRDSVRQALRGGITAEQIVSYLEQYAHPNMRMVESAIHSKSCLPPTVVDQIKLWEL 432
            |.::.||::||:|||.||:.||||.||:|:|...|||........:   :|||.||.|||:|||.
 Worm   345 FQDMSVGMITRESVRGALQHGITAAQIISFLRANAHPQCIATSGPV---NCLPITVADQIRLWED 406

  Fly   433 ERNRFTYTEGVLYNQFLSHTDFVTLRDYAQSIHMLVWQNERTRTMVVQKNGHDDVKRYWKK-YSK 496
            ||.|....:..:|:.|.|..:|..:.:||:..::|:|.:.:.:.::|.::||:.|::::|: .||
 Worm   407 ERRRMNLKDAYIYSHFESEDEFHGVCEYARQQNILLWSDNQQKLVIVNEDGHELVRQWYKREKSK 471

  Fly   497 SG 498
            :|
 Worm   472 TG 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mrn	NP_648780.1	Tfb2	39..404	CDD:461075	118/387 (30%)
		Tfb2_C	425..492	CDD:465701	21/66 (32%)
gtf-2H4	NP_001263824.1	Tfb2	25..381	CDD:461075	118/387 (30%)
		Tfb2_C	399..466	CDD:465701	21/66 (32%)