Protein Alignment mrn and Gtf2h4

DIOPT Version :10

• Sequence 1: NP_648780.1
• Gene: mrn / 39688
• FlyBaseID: FBgn0261109
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_034494.1
• Gene: Gtf2h4 / 14885
• MGIID: 1338799
• Length: 463
• Species: Mus musculus
• Alignment Length: 474
• Identity: 242/474 - (51%)
• Similarity: 322/474 - (67%)
• Gaps: 22/474 - (4%)

  Fly    26 GQGPANLECKDFQEYLRTRQTPESLEKLYNYPPICLAVFRELPEIARQFIIRILFVDQPVPQAVV 90
            |...|:|:|::.||:| ...:|..|::||.:|..|||||||||.:|:.:::|:||::||:|||.|
Mouse     9 GLNRAHLQCRNLQEFL-GGLSPGVLDRLYGHPATCLAVFRELPSLAKNWVMRMLFLEQPLPQAAV 72

  Fly    91 TSWGAQRCAKEQAEATSCLTALNVWRVTAIPGGLSAWELSPTFKKSVRQVLLGGGKPW-PMTNTL 154
            ..|..:..:|.|.|:|..|:.|.:|....:||||....|:|.|::::|..||||||.| ..|:.|
Mouse    73 ALWVKKEFSKAQEESTGLLSGLRIWHTQLLPGGLQGLILNPVFRQNLRIALLGGGKAWSDDTSQL 137

  Fly   155 DKDSKPRDIAFLDTYAMSRWRCVLHYMVGTGNRNGTDAEAISPDAVRILLHANLMKRDE-RDGIT 218
            ..|...||:..||.||..||..|||:||      |:.:.|:|.|..::|..|.|||..| .:...
Mouse   138 GPDKHARDVPSLDKYAEERWEVVLHFMV------GSPSAAVSQDLAQLLSQAGLMKSTEPGEPPC 196

  Fly   219 ITRQGFQFLLLDTRAQVWHFMLQYLDTCEERGISLPECLSMLFQLSFSTLGRDYSSEGMNSQMLT 283
            ||..|||||||||.||:|:||||||.|.:.||:.|.|.||.||||||||||:|||.|||:..:|.
Mouse   197 ITSAGFQFLLLDTPAQLWYFMLQYLQTAQSRGMDLVEILSFLFQLSFSTLGKDYSVEGMSDSLLN 261

  Fly   284 FLQHLREFGLVFQRKRKEGRFYPTRLALNVTSKEAAATASVAMDEEATQDCGYIVVETNYRVYAY 348
            |||||||||||||||||..|:||||||:|::|..:.|..:|       ...|:||||||||:|||
Mouse   262 FLQHLREFGLVFQRKRKSRRYYPTRLAINLSSGVSGAGGTV-------HQPGFIVVETNYRLYAY 319

  Fly   349 TDSPLQVAVLGLFTELLYRFPNLVVGVLTRDSVRQALRGGITAEQIVSYLEQYAHPNMRMVESAI 413
            |:|.||:|::.||:|:||||||:||..:||:||:||:..||||:||:.:|...|||.|      :
Mouse   320 TESELQIALIALFSEMLYRFPNMVVAQVTRESVQQAIASGITAQQIIHFLRTRAHPVM------L 378

  Fly   414 HSKSCLPPTVVDQIKLWELERNRFTYTEGVLYNQFLSHTDFVTLRDYAQSIHMLVWQNERTRTMV 478
            .....||||:.|||:||||||:|..:|||||||||||..||..|..:|:.:.:||::|...|.||
Mouse   379 KQNPVLPPTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFELLLAHARELGVLVFENSAKRLMV 443

  Fly   479 VQKNGHDDVKRYWKKYSKS 497
            |...||.||||:||:...|
Mouse   444 VTPAGHSDVKRFWKRQKHS 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mrn	NP_648780.1	Tfb2	39..404	CDD:461075	189/366 (52%)
		Tfb2_C	425..492	CDD:465701	38/66 (58%)
Gtf2h4	NP_034494.1	tfb2	19..461	CDD:273180	237/461 (51%)