Protein Alignment AGO2 and AGO9

DIOPT Version :10

• Sequence 1: NP_730054.1
• Gene: AGO2 / 39683
• FlyBaseID: FBgn0087035
• Length: 1217
• Species: Drosophila melanogaster
• Sequence 2: NP_197613.2
• Gene: AGO9 / 832241
• AraportID: AT5G21150
• Length: 896
• Species: Arabidopsis thaliana
• Alignment Length: 869
• Identity: 220/869 - (25%)
• Similarity: 381/869 - (43%)
• Gaps: 137/869 - (15%)

  Fly   398 LPLPPQPAGSIKRGTIGKPGQVGINYLDLDLSKMPSVAYHYDVKIMPE--RP-------KKFYRQ 453
            ||: .:|.||   |:.|:...:..|:..:..:|.....:||.|.|..|  ||       :|...:
plant    35 LPM-ARPRGS---GSKGQKIPLLTNHFGVKFNKPSGYFFHYSVAINYEDGRPVEAKGIGRKILDK 95

  Fly   454 AFEQFRVDQLGGAVLAYDGKASCYSVDKLPLNSQNPEVTVTD---------------------RN 497
            ..|.::.| ||....||||:.:.::|..||.|..:..|.:.:                     |.
plant    96 VQETYQSD-LGAKYFAYDGEKTLFTVGALPSNKLDFSVVLEEIPSSRNHAGNDTNDADRKRSRRP 159

  Fly   498 GRTLRYTIEIKETGDSTIDLKSLTTYMNDRIFDKPMRAMQCVEVVL-ASPCHNKAIRVGRSFFKM 561
            .:|.::.:||...  :.|.::::.:.:..:..:....|::.::::| .|......:.|.:|||.
plant   160 NQTKKFMVEISYA--AKIPMQAIASALQGKETENLQDALRVLDIILRQSAARQGCLLVRQSFFH- 221

  Fly   562 SDPNNRHELDDGYEALVGLYQAFMLGDRPF-LNVDISHKSFPISMPMIEYLERFSLKAKINNTTN 625
            :|..|...:..|.....|.:.:|....... ||:|.|........|::::|.....|   .:...
plant   222 NDVKNFVPIGGGVSGCRGFHSSFRTTQGGLSLNIDTSTTMIVQPGPVVDFLLANQNK---KDPYG 283

  Fly   626 LDYSRRFLEPFLRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETF---------EHDGKKVTI 681
            :|:::  ....|:.:.|..|      .:.|.|:::|||......:.|         |.:..::|:
plant   284 MDWNK--ARRVLKNLRVQIT------LSNREYKISGLSEHSCKDQLFTWRKPNDKGEFEEVEITV 340

  Fly   682 ASYFHSRN----YPLKFPQLHCLNVGSSIKSILLPIELCSIEEGQALNRKDGATQVANMIKYAAT 742
            .:|:..||    |...||   |:|||...:....|||.|::...|...:.....|.|.:::.:..
plant   341 LNYYKERNIEVRYSGDFP---CINVGKPKRPTYFPIEFCNLVSLQRYTKSLTNFQRAALVEKSRQ 402

  Fly   743 STNVRKRKIMNLLQYFQHNLDPTISRFGIRIANDFIVVSTRVLSPPQVEY-HSKRFTMVKNGSWR 806
            ....|...:...|:...:|.||.:...|:.|..:|..|..|:|..|.::. ..:..:.:| |.|.
plant   403 KPPERMASLTKGLKDSNYNADPVLQDSGVSIITNFTQVEGRILPTPMLKVGKGENLSPIK-GKWN 466

  Fly   807 MDGMKFLEPKPKAHKCAVLY---CDPRSGRKMNYTQLNDFGNLIISQGKAVNISLDSDVTYRPFT 868
            .......||........|.:   ||..       |.:.|    :|..|:...|:::.     ||.
plant   467 FMRKTLAEPTTVTRWAVVNFSARCDTN-------TLIRD----LIKCGREKGINVEP-----PFK 515

  Fly   869 D--DER----------SLDTIFADLKRS--QHDLAIVIIPQFRISYDTI---KQKAELQHGILTQ 916
            |  :|.          .::.:|..:|..  :..|.::.|...|.:.|..   |:|..:..||:||
plant   516 DVINENPQFRNAPATVRVENMFEQIKSKLPKPPLFLLCILAERKNSDVYGPWKKKNLVDLGIVTQ 580

  Fly   917 CIKQFTVERKCNNQTIGNILLKINSKLNGINH--KIKDDPRLPMMKN--TMYIGADVTHPSPDQR 977
            ||    ...:.|:|.:.|:|||||:||.|:|.  .::..|.:|.:..  |:.:|.||:|.||.|.
plant   581 CI----APTRLNDQYLTNVLLKINAKLGGLNSLLAMERSPAMPKVTQVPTIIVGMDVSHGSPGQS 641

  Fly   978 EIPSVVGVAASHD-PYGASYNMQYRLQRGALEEIEDMF------------SITLEHLRVYKEYRN 1029
            :|||:..|.:|.. |..:.|....|.|...:|.|:::|            .:.|:   .|....|
plant   642 DIPSIAAVVSSRQWPLISKYKACVRTQSRKMEMIDNLFKPVNGKDEGMFRELLLD---FYYSSEN 703

  Fly  1030 AYPDHIIYYRDGVSDGQFPKIKNEELRCIKQACDKVG--CKPKICCVIVVKRHHTRFFPSGDVTT 1092
            ..|:|||.:|||||:.||.::.|.||..:.|||..:.  ..||...::..|.|||:||.|...
plant   704 RKPEHIIIFRDGVSESQFNQVLNIELDQMMQACKFLDDTWHPKFTVIVAQKNHHTKFFQSRGP-- 766

  Fly  1093 SNKFNNVDPGTVVDRTIVHPNEMQFFMVSHQAIQGTAKPTRYNVIENTGNLDIDLLQQLTYNLCH 1157
                :||.|||::|..|.||....|::.:|..:.||.:||.|:|:.:......|.||:|.::|.:
plant   767 ----DNVPPGTIIDSQICHPRNFDFYLCAHAGMIGTTRPTHYHVLYDEIGFATDDLQELVHSLSY 827

  Fly  1158 MFPRCNRSVSYPAPAYLAHLVAAR 1181
            ::.|...::|..||...|||.||:
plant   828 VYQRSTTAISVVAPVCYAHLAAAQ 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AGO2	NP_730054.1	ArgoN	471..543	CDD:465134	13/92 (14%)
		ArgoL1	554..601	CDD:462567	13/47 (28%)
		PAZ	605..719	CDD:239207	29/126 (23%)
		Piwi_ago-like	764..1186	CDD:240015	133/458 (29%)
AGO9	NP_197613.2	PLN03202	17..896	CDD:215631	220/869 (25%)