Protein Alignment Pdi and tmx3

DIOPT Version :9

• Sequence 1: NP_524079.1
• Gene: Pdi / 39651
• FlyBaseID: FBgn0286818
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_002939661.2
• Gene: tmx3 / 100493559
• XenbaseID: XB-GENE-946768
• Length: 454
• Species: Xenopus tropicalis
• Alignment Length: 362
• Identity: 88/362 - (24%)
• Similarity: 165/362 - (45%)
• Gaps: 48/362 - (13%)

  Fly     9 FLAASYVAASAEAEVKVEEGVLVATV-DNFKQLIADNEFVLVEFYAPWCGHCKALAPEYAKAAQQ 72
            |:.|:..:.|..|.:.|  ..||..: |:||:...| :..||:||||||||||.|.|.:.:...:
 Frog     8 FILATVASTSLLASLPV--SALVEDLDDSFKENRKD-DIWLVDFYAPWCGHCKKLEPVWNEVGIE 69

  Fly    73 LAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGSPVEYSGGRQAADIIAWVTKKTGPPA 137
            :....|||::.|:||||...:|.::.|||:||:|..:......|.|.|...||:.:..:..||..
 Frog    70 MRSSGSPIRVGKMDATVHSSIASEFGVRGFPTIKVLKGDMAYNYRGPRTKEDIVEFANRVAGPLI 134

  Fly   138 KDLTSVADAEQFLKDNEIAIIGFFKDLESEEAKTFTKVANALDSFVFGVSSNADVIAKYEA---- 198
            :.|.|....:...|.:.:..:  :..:||...:.:.:||:.|..:.:..|::.||:.||..
 Frog   135 RPLPSQQMFDHVQKRHSVLFV--YVGVESTLKEKYIEVASELIVYTYFFSASEDVLPKYVTLNEV 197

  Fly   199 ------KDNGVVLFKPFDDKKSVFEGEL----NEENLKKFAQVQSLPLIVDFNHESASKIFGGSI 253
                  ||:...::..::|      |:|    |:|..:.:..:....|     :|     .|.:.
 Frog   198 PAVLVFKDSTYFVYDEYED------GDLSSWVNKERFEGYLHIDGFTL-----YE-----LGDTG 246

  Fly   254 KSHLLFFVSREGGHIE--KYVDPLKEIAKKYRD----DILFVTISSDEEDHTRIFEFFGMNKEEV 312
            |...:..:..:...:|  :.....:::||.|||    |..|..:..::..::.:     |::..:
 Frog   247 KLVAVAVIDEKNNSVEHTRLKSIAQDVAKNYRDHFHRDFQFGHMDGNDYINSLL-----MDELSI 306

  Fly   313 PTIRLIKLEEDMAKYKPESDDLSAETIEAFLKKFLDG 349
            ||..::. ..:...:.|.....:.|.:..|:...|||
 Frog   307 PTFVVLN-TSNQQYFLPSKQIENTEEMIQFINSILDG 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdi	NP_524079.1	ER_PDI_fam	27..474	CDD:273457	83/344 (24%)
tmx3	XP_002939661.2	PDI_a_TMX3	27..130	CDD:239298	40/103 (39%)
		ER_PDI_fam	29..>346	CDD:273457	81/339 (24%)