Protein Alignment: CG12316 and Msl1

• Sequence 1: NP_648752.1
• Gene: CG12316
• FlyBaseID: FBgn0036483
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_082998.2
• Gene: Msl1
• MGIID: 1921276
• Length: 616
• Species: Mus musculus
• Alignment Length: 713
• Identity: 126/714 (18%)
• Similarity: 213/714 (30%)
• Gaps: 241/714 (34%)

  Fly   487 QTLDDEEQDLV--EEDQYSGAHSHGFFPRSSN--------ASYASGQRTP-------------LY 528
            |.||.|....:  .||:...|.:| |.||...        ||...|..:|             |.
Mouse    21 QRLDYERAAALGGPEDESGAAEAH-FLPRHRKLKEPGPPLASSQGGSPSPSPAGCGGGKGRGLLL 84

  Fly   529 HCRQTSSQNSNCSESSL-------LKKQVTFSPRHLGAATPNAKTGTSKKPSIKQYKPSSSNATE 586
            .......|.......|:       ..||.     .:|.....|..|.|.:|..:...|..:.:..
Mouse    85 PAGAAPGQQEESWGGSVPLPCPPPATKQA-----GIGGEPVAAGAGCSPRPKYQAVLPIQTGSIV 144

  Fly   587 SQRWKEEHRKASAKMFAKLDAKIKARSEAENVSTSQLTPTTSNASSSTPTKISGTPTRIRSTQRG 651
            ....||....|..|..|...|                 .|.|:.:...|..:.|.|.
Mouse   145 VAAAKEPTPWAGDKGGAAPPA-----------------ATASDPAGPPPLPLPGPPP-------- 184

  Fly   652 QRVALPTPPASTHSSSSP--CQIRSASTDNHNYNVDSDYSRRCFSKAAGDEVSYYNHLLTLQREN 714
               ..||..|.|.::|..  ..||.:......            ...|..:.:....:|.||.:.
Mouse   185 ---LAPTATAGTLAASEGRWKSIRKSPLGGGG------------GSGASSQAACLKQILLLQLDL 234

  Fly   715 IRRRRLNNQKKKKNRKVSQKVQKKDDKLNMLKQATKRCRKLRALNAKRK---------------- 763
            |.:::  .|.:.|.:::.:...::|..|..:::..:|.:.::..|.|.:
Mouse   235 IEQQQ--QQLQAKEKEIEELKSERDTLLARIERMERRMQLVKRDNEKERHKLLQGYEPEEREEAE 297

  Fly   764 -NEVQKLEQDLDTIRKS-------------------------APHKLPIIRL----KRCNLKTQK 798
             :|..|||:..:....|                         ...|.|:.:|    .:...||.|
Mouse   298 LSEKIKLERQPELCETSQALPSKPFSCGRSGKGHKRKTPFGNTERKTPVKKLAPEFSKVKTKTPK 362

  Fly   799 RS-LKAEEAPSVQEDILSMNSDRELQEQKKAQKPKRKRYKKVQKEQENEKYLREQEIIISQSQMV 862
            .| :|.|...|:.|.:..    |||:.|:..:||:..                    :.:..::.
Mouse   363 HSPIKEEPCGSISETVCK----RELRSQETPEKPRSS--------------------VDTPPRLS 403

  Fly   863 EEDKVEEHHAHEAPSEQQRELDLEHQQFLE--EQLLQEEHQ-----LAMHEEEHHQMDDEQESHE 920
            ...|....|    |.|:....::|...:|.  |..|...||     |.:.|      ...::...
Mouse   404 TPQKGPSTH----PKEKAFSSEMEDLPYLSTTEMYLCRWHQPPPSPLPLRE------SSPKKEET 458

  Fly   921 VARLLEDQQPAEGTHLHVENEMLAEKEQPLIEDDDQEADDQNQNEHLSDDQQQEADQQLSIEQPQ 985
            |||.|.....|..|.:...........:||     ::.:..:..|:|.|....:...:|.:::
Mouse   459 VARCLMPSSVAGETSVLAVPSWRDHSVEPL-----RDPNPSDILENLDDSVFSKRHAKLELDE-- 516

  Fly   986 EHEENQSLSQDPLDEQCTPTPNGKRRK-------RRRRFKRRCWTHVKNKKKKQWLIDYPLEFEA 1043
                                   ||||       |.:|..:|....:..||..|         |:
Mouse   517 -----------------------KRRKRWDIQRIREQRILQRLQLRMYKKKGIQ---------ES 549

  Fly  1044 DPALDTPPIQPEPAPDEQQAELVTGPVSESVAEPVAEPVAEPVSEPFAEQIAEPIAQPTPEPA 1106
            :|  :.....||  ||:.::.|:|                     ||...:|  ..:|.|:.|
Mouse   550 EP--EVTSFFPE--PDDVESLLIT---------------------PFLPVVA--FGRPLPKLA 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12316	NP_648752.1	PHA02666	504..>685	CDD:222914	38/211 (18%)
		GBP_C	<819..947	CDD:303769	24/135 (18%)
		coiled coil	931..943	CDD:293879	2/12 (17%)
		Trypan_PARP	<1026..1130	CDD:114603	17/82 (21%)
Msl1	NP_082998.2	Interaction with MSL2. {ECO:0000250}	225..239		4/14 (29%)
		PEHE	477..593	CDD:291924	30/176 (17%)
		Interaction with KAT8. {ECO:0000269|PubMed:21217699}	500..520		6/45 (13%)
		Interaction with MSL3 MRG domain	552..593		12/60 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C132177571
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR21656
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030