Protein Alignment CG12316 and msl-1

DIOPT Version :10

• Sequence 1: NP_648752.1
• Gene: CG12316 / 39650
• FlyBaseID: FBgn0036483
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_476896.1
• Gene: msl-1 / 35121
• FlyBaseID: FBgn0005617
• Length: 1039
• Species: Drosophila melanogaster
• Alignment Length: 555
• Identity: 117/555 - (21%)
• Similarity: 210/555 - (37%)
• Gaps: 151/555 - (27%)

  Fly   708 LTLQRENIRRR-RLN-NQKKKKNRKVSQKVQKKDD---KLNM-------LKQATKR--------C 752
            |..:..|:||. .|| |..:::...::.|.::.||   |:::       ||||..:        |
  Fly   103 LISENNNLRRMVMLNLNLMQEQTDSIAAKDKELDDQSAKMSVVKAQNEELKQAVAQLEAANQELC 167

  Fly   753 RKLRALNAKRKNEVQKLEQDLDTIRKSAPHKLPIIRLKRCNLKTQ-------------------- 797
            ::||..|.:|.      :.|.|......|...|..:|.||:.:||
  Fly   168 KQLRRKNQRRN------DNDDDDDDPPLPPAAPQQKLIRCHAETQTVFREREQGTQTIDAQPQFA 226

  Fly   798 ---KRSLKAEEAPSVQEDILSMNSDRELQEQKKAQKPKRKRYKKVQKEQENEKYLREQEIIISQS 859
               .|.:..:|:|::.....::.:           :|..||.:...:.:.|.|  :....|:
  Fly   227 NALPRGINMKESPALDHHAGAVTN-----------QPASKRSESKGRGEFNGK--KVSTFIL--- 275

  Fly   860 QMVEEDKVEEHHAHEAPSEQQRELDLEHQ-QFLEEQLLQEEHQLAMHEEEHHQMDDEQESHEVAR 923
            |.:.:|  .|||.||     |.|:..||: :..:||:.|||.||...|:..|..:...|......
  Fly   276 QRMNQD--FEHHIHE-----QTEVAEEHEMEAHKEQISQEEDQLVAEEDHLHMQEVHTEEVVGGD 333

  Fly   924 LLEDQQPAEGTHLHVENEMLAEKEQ--------PLIEDDDQEADDQNQNEHLSDDQQQ------- 973
            :..|  ..|...:.|..|.|.:.|:        ..||:||.|.|:.::|....||.::
  Fly   334 IFHD--ALESIEMEVVTEELVDMEEHGQSVDANGHIEEDDDEDDEDDENSDKDDDSEEDDYPWMH 396

  Fly   974 -EADQQLSIEQPQEHEENQSLSQDPLDEQ-CTP----TPNGKRRKRRRRFKRRCWTHVKNKKKKQ 1032
             :||.....|:.....:|..|..||.:|: |.|    |||.:::...:       ..::.:..:.
  Fly   397 SDADVNARTEEELWQNQNYLLELDPTEEKTCAPSAHSTPNHQQKSSTQ-------AEIRKEGNQN 454

  Fly  1033 WLIDYPLEFEADPALDT--PPIQPEPAPDEQQAELVTGPVSESVAEPVAEPVAEPVSEPFAE--- 1092
            .:.:..|:.:.:|.:|.  .||.|         :.|.....:...|.|.|....|..:|..|
  Fly   455 RITEKLLQLKPEPMVDALEAPILP---------KWVAFKKKDKEHESVPESPEVPKQQPHQEDAI 510

  Fly  1093 ----------QIAEPIAQPTPEPAYDFDQDLVPEVGNELEIAAPIRVAEDEDSTAIL-------- 1139
                      ::.:|..:|..:|..:..||      .:|:    :||...||...:.
  Fly   511 VDHNAIKNQLEVPKPDLKPKDQPKDEQRQD------GQLD----VRVEPQEDVRKVQKETLKRQP 565

  Fly  1140 --SPSHNLELVTSHVPVYLLNGESRDVSTPLSSSS 1172
              :|.|..:.|...|    ....||:.:.|.::::
  Fly   566 EDAPKHLPKAVAPKV----TKTSSRESTLPKANTA 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12316	NP_648752.1	PHA02666	504..>685	CDD:222914
		PTZ00121	<732..995	CDD:173412	72/320 (23%)
		PTZ00341	<804..>926	CDD:173534	29/122 (24%)
		PRK10819	1051..>1105	CDD:236768	12/66 (18%)
msl-1	NP_476896.1	PspC_subgroup_1	<447..>583	CDD:468201	27/158 (17%)
		PEHE	866..983	CDD:464607