Protein Alignment: CG12316 and MSL1

• Sequence 1: NP_648752.1
• Gene: CG12316
• FlyBaseID: FBgn0036483
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_001352848.1
• Gene: MSL1
• HGNCID: 27905
• Length: 614
• Species: Homo sapiens
• Alignment Length: 726
• Identity: 123/727 (17%)
• Similarity: 216/727 (30%)
• Gaps: 269/727 (37%)

  Fly   487 QTLDDEEQDLV--EEDQYSGAHSHGFFPRSSN--------ASYASGQRTP------------LYH 529
            |.||.|....:  .||:...|.:| |.||...        ||...|...|            |..
Human    21 QRLDYERAAALGGPEDEPGAAEAH-FLPRHRKLKEPGPPLASSQGGSPAPSPAGCGGKGRGLLLP 84

  Fly   530 CRQTSSQNSN---------CSESSLLKKQVTFSPRHLGAATPNAKTGTSKKPSIKQYKPSSSN-- 583
            ......|...         |...:..:..:...|...||       |.|.:|..:...|..:.
Human    85 AGAAPGQQEESWGGSVPLPCPPPATKQAGIGGEPAAAGA-------GCSPRPKYQAVLPIQTGSL 142

  Fly   584 ---ATESQRWKEEHRKASAKMFAKLDAKIKARSEAENVSTSQLTPTTSNASSSTPTKISGTPTRI 645
               |.|...|..:...|::.                       ..|.|:.:...|..:.|.|.
Human   143 VAAAKEPTPWAGDKGGAASP-----------------------AATASDPAGPPPLPLPGPPP-- 182

  Fly   646 RSTQRGQRVALPTPPASTHSSS---------SPCQIRSASTDNHNYNVDSDYSRRCFSKAAGDEV 701
                     ..||..|.|.::|         ||......|                   .|..:.
Human   183 ---------LAPTATAGTLAASEGRWKSMRKSPLGGGGGS-------------------GASSQA 219

  Fly   702 SYYNHLLTLQRENIRRRRLNNQKKKKNRKVSQKVQKKDDKLNMLKQATKRCRKLRALNAKRKNEV 766
            :....:|.||.:.|.:::  .|.:.|.:::.:...::|..|..:::..:|.:.::..|.|.::::
Human   220 ACLKQILLLQLDLIEQQQ--QQLQAKEKEIEELKSERDTLLARIERMERRMQLVKKDNEKERHKL 282

  Fly   767 -----------------------QKLEQDLDTI---------------RK----SAPHKLPIIRL 789
                                   .:|.:...|:               ||    |...|.|:.:|
Human   283 FQGYETEEREETELSEKIKLECQPELSETSQTLPPKPFSCGRSGKGHKRKSPFGSTERKTPVKKL 347

  Fly   790 ----KRCNLKTQKRS-LKAEEAPSVQEDILSMNSDRELQEQKKAQKPKRKRYKKVQKEQENEKYL 849
                .:...||.|.| :|.|...|:.|.:..    |||:.|:..:||:..
Human   348 APEFSKVKTKTPKHSPIKEEPCGSLSETVCK----RELRSQETPEKPRSS--------------- 393

  Fly   850 REQEIIISQSQMVEEDKVEEHHAHEAPSEQQRELDLEHQQFLE--EQLLQEEHQ-----LAMHEE 907
                 :.:..::....|....|    |.|:....::|...:|.  |..|...||     |.:.|
Human   394 -----VDTPPRLSTPQKGPSTH----PKEKAFSSEIEDLPYLSTTEMYLCRWHQPPPSPLPLRE- 448

  Fly   908 EHHQMDDEQESHEVARLLEDQQPAEGTHLHVENEMLAEKEQPLIEDDDQEADDQNQNEHLSDDQQ 972
                 ...::...|||.|.....|..|.:...........:||     ::.:..:..|:|.|...
Human   449 -----SSPKKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPL-----RDPNPSDLLENLDDSVF 503

  Fly   973 QEADQQLSIEQPQEHEENQSLSQDPLDEQCTPTPNGKRRK-------RRRRFKRRCWTHVKNKKK 1030
            .:...:|.:::                         ||||       |.:|..:|....:..||.
Human   504 SKRHAKLELDE-------------------------KRRKRWDIQRIREQRILQRLQLRMYKKKG 543

  Fly  1031 KQWLIDYPLEFEADPALDTPPIQPEPAPDEQQAELVTGPVSESVAEPVAEPVAEPVSEPFAEQIA 1095
            .|         |::|  :.....||  ||:.::.::|                     ||...:|
Human   544 IQ---------ESEP--EVTSFFPE--PDDVESLMIT---------------------PFLPVVA 574

  Fly  1096 --EPIAQPTPE 1104
              .|:.:.||:
Human   575 FGRPLPKLTPQ 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12316	NP_648752.1	PHA02666	504..>685	CDD:222914	36/224 (16%)
		GBP_C	<819..947	CDD:303769	24/135 (18%)
		coiled coil	931..943	CDD:293879	2/12 (17%)
		Trypan_PARP	<1026..1130	CDD:114603	16/82 (20%)
MSL1	NP_001352848.1	Interaction with MSL2	223..237		4/14 (29%)
		TOP2c	<243..429	CDD:330395	34/214 (16%)
		PEHE	475..591	CDD:317651	29/176 (16%)
		Interaction with KAT8	498..518		6/45 (13%)
		Sufficient for interaction with MSL3 MRG domain	550..591		11/60 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C132165438
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR21656
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.030